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Preexisting endothelial cells mediate cardiac neovascularization after injury.
He L, Huang X, Kanisicak O, Li Y, Wang Y, Li Y, Pu W, Liu Q, Zhang H, Tian X, Zhao H, Liu X, Zhang S, Nie Y, Hu S, Miao X, Wang QD, Wang F, Chen T, Xu Q, Lui KO, Molkentin JD, Zhou B. He L, et al. J Clin Invest. 2017 Aug 1;127(8):2968-2981. doi: 10.1172/JCI93868. Epub 2017 Jun 26. J Clin Invest. 2017. PMID: 28650345 Free PMC article.
Here, we show that preexisting endothelial cells mainly beget new coronary vessels in the adult mouse heart, with essentially no contribution from other cell sources through cell-lineage transdifferentiation. ...Instead, preexisting endotheli
Here, we show that preexisting endothelial cells mainly beget new coronary vessels in the adult mouse heart, wit …
The Development and Regeneration of Coronary Arteries.
He L, Zhou B. He L, et al. Curr Cardiol Rep. 2018 May 25;20(7):54. doi: 10.1007/s11886-018-0999-2. Curr Cardiol Rep. 2018. PMID: 29802591 Review.
Recently, fibroblasts were reported to contribute to endothelial cells after cardiac injury through mesenchymal-to-endothelial transition. A subsequent study demonstrated that pre-existing endothelial cells mainly mediate
Recently, fibroblasts were reported to contribute to endothelial cells after cardiac injury through mesenchymal- …
Non-coding RNAs in endothelial cell signalling and hypoxia during cardiac regeneration.
Peters MMC, Sampaio-Pinto V, da Costa Martins PA. Peters MMC, et al. Biochim Biophys Acta Mol Cell Res. 2020 Mar;1867(3):118515. doi: 10.1016/j.bbamcr.2019.07.010. Epub 2019 Jul 27. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 31362011 Free article. Review.
Cardiac regeneration is considered to be mediated by proliferation of pre-existing cardiomyocytes (CMs) mainly located in a hypoxic niche. ...In this review, we highlight the molecular interactions between endothelial cells (ECs) and CMs in cardiac
Cardiac regeneration is considered to be mediated by proliferation of pre-existing cardiomyocytes (CMs) mainly located in a hy