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Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia.
Rock MJ, Prenen J, Funari VA, Funari TL, Merriman B, Nelson SF, Lachman RS, Wilcox WR, Reyno S, Quadrelli R, Vaglio A, Owsianik G, Janssens A, Voets T, Ikegawa S, Nagai T, Rimoin DL, Nilius B, Cohn DH. Rock MJ, et al. Among authors: prenen j. Nat Genet. 2008 Aug;40(8):999-1003. doi: 10.1038/ng.166. Epub 2008 Jun 29. Nat Genet. 2008. PMID: 18587396 Free PMC article.
TRPV4 calcium entry channel: a paradigm for gating diversity.
Nilius B, Vriens J, Prenen J, Droogmans G, Voets T. Nilius B, et al. Among authors: prenen j. Am J Physiol Cell Physiol. 2004 Feb;286(2):C195-205. doi: 10.1152/ajpcell.00365.2003. Am J Physiol Cell Physiol. 2004. PMID: 14707014 Free article. Review.
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3.
D'hoedt D, Owsianik G, Prenen J, Cuajungco MP, Grimm C, Heller S, Voets T, Nilius B. D'hoedt D, et al. Among authors: prenen j. J Biol Chem. 2008 Mar 7;283(10):6272-80. doi: 10.1074/jbc.M706386200. Epub 2008 Jan 3. J Biol Chem. 2008. PMID: 18174177 Free article.
Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity.
Klausen TK, Janssens A, Prenen J, Owsianik G, Hoffmann EK, Pedersen SF, Nilius B. Klausen TK, et al. Among authors: prenen j. Cell Calcium. 2014 Jan;55(1):38-47. doi: 10.1016/j.ceca.2013.11.001. Epub 2013 Nov 21. Cell Calcium. 2014. PMID: 24342753
Molecular determinants of permeation through the cation channel TRPV4.
Voets T, Prenen J, Vriens J, Watanabe H, Janssens A, Wissenbach U, Bödding M, Droogmans G, Nilius B. Voets T, et al. Among authors: prenen j. J Biol Chem. 2002 Sep 13;277(37):33704-10. doi: 10.1074/jbc.M204828200. Epub 2002 Jul 1. J Biol Chem. 2002. PMID: 12093812 Free article.
75 results