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1988 1
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Preoperative oral antibiotics and surgical-site infections in colon surgery (ORALEV): a multicentre, single-blind, pragmatic, randomised controlled trial.
Espin Basany E, Solís-Peña A, Pellino G, Kreisler E, Fraccalvieri D, Muinelo-Lorenzo M, Maseda-Díaz O, García-González JM, Santamaría-Olabarrieta M, Codina-Cazador A, Biondo S. Espin Basany E, et al. Lancet Gastroenterol Hepatol. 2020 Aug;5(8):729-738. doi: 10.1016/S2468-1253(20)30075-3. Epub 2020 Apr 21. Lancet Gastroenterol Hepatol. 2020. PMID: 32325012 Clinical Trial.
BACKGROUND: Previous studies have found that mechanical bowel preparation with oral antibiotics can reduce the incidence of surgical-site infections, but no randomised controlled trial has assessed oral antibiotics alone without me …
BACKGROUND: Previous studies have found that mechanical bowel preparation with oral antibiotics can reduce the incidenc …
Preoperative oral antibiotic bowel preparation in elective resectional colorectal surgery reduces rates of surgical site infections: a single-centre experience with a cost-effectiveness analysis.
Vadhwana B, Pouzi A, Surjus Kaneta G, Reid V, Claxton D, Pyne L, Chalmers R, Malik A, Bowers D, Groot-Wassink T. Vadhwana B, et al. Ann R Coll Surg Engl. 2020 Feb;102(2):133-140. doi: 10.1308/rcsann.2019.0117. Epub 2019 Sep 11. Ann R Coll Surg Engl. 2020. PMID: 31508999 Clinical Trial.
INTRODUCTION: Surgical site infections cause considerable postoperative morbidity and mortality. The aim of this study was to determine the effect on surgical site infection rates following introduction of a departmental oral an
INTRODUCTION: Surgical site infections cause considerable postoperative morbidity and mortality. The aim of this study was to …
Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections.
Golder AM, Steele CW, Conn D, MacKay GJ, McMillan DC, Horgan PG, Roxburgh CS, McSorley ST. Golder AM, et al. BJS Open. 2019 Oct 16;3(6):830-839. doi: 10.1002/bjs5.50224. eCollection 2019 Dec. BJS Open. 2019. PMID: 31832590 Free PMC article. Clinical Trial.
BACKGROUND: Preoperative oral antibiotics in addition to intravenous antibiotics and mechanical bowel preparation (MBP) may influence the gut microbiome and reduce both the postoperative systemic inflammatory response to surgery and postoperativ …
BACKGROUND: Preoperative oral antibiotics in addition to intravenous antibiotics and mechanical bowel preparatio …
Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections.
Cannon JA, Altom LK, Deierhoi RJ, Morris M, Richman JS, Vick CC, Itani KM, Hawn MT. Cannon JA, et al. Dis Colon Rectum. 2012 Nov;55(11):1160-6. doi: 10.1097/DCR.0b013e3182684fac. Dis Colon Rectum. 2012. PMID: 23044677 Clinical Trial.
BACKGROUND: Surgical site infection is a major cause of morbidity after colorectal resections. Despite evidence that preoperative oral antibiotics with mechanical bowel preparation reduce surgical site
BACKGROUND: Surgical site infection is a major cause of morbidity after colorectal resections. Despite ev …
A prospective, randomized trial of perioperative prophylactic cefamandole in elective colorectal surgery for malignancy.
Petrelli NJ, Conte CC, Herrera L, Stulc J, O'Neill P. Petrelli NJ, et al. Dis Colon Rectum. 1988 Jun;31(6):427-9. doi: 10.1007/BF02552610. Dis Colon Rectum. 1988. PMID: 3378465 Clinical Trial.
The Dukes stage was similar and the surgical procedures were equally distributed in the two groups. There were no wound infections in the 34 patients receiving cefamandole and only one wound infection (2.8 percent) in the 36 control patients. Th …
The Dukes stage was similar and the surgical procedures were equally distributed in the two groups. There were no wound
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