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High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.
Shields RL, Namenuk AK, Hong K, Meng YG, Rae J, Briggs J, Xie D, Lai J, Stadlen A, Li B, Fox JA, Presta LG. Shields RL, et al. Among authors: presta lg. J Biol Chem. 2001 Mar 2;276(9):6591-604. doi: 10.1074/jbc.M009483200. Epub 2000 Nov 28. J Biol Chem. 2001. PMID: 11096108 Free article.
An efficient route to human bispecific IgG.
Merchant AM, Zhu Z, Yuan JQ, Goddard A, Adams CW, Presta LG, Carter P. Merchant AM, et al. Among authors: presta lg. Nat Biotechnol. 1998 Jul;16(7):677-81. doi: 10.1038/nbt0798-677. Nat Biotechnol. 1998. PMID: 9661204
Design, construction, and in vitro analyses of multivalent antibodies.
Miller K, Meng G, Liu J, Hurst A, Hsei V, Wong WL, Ekert R, Lawrence D, Sherwood S, DeForge L, Gaudreault J, Keller G, Sliwkowski M, Ashkenazi A, Presta L. Miller K, et al. J Immunol. 2003 May 1;170(9):4854-61. doi: 10.4049/jimmunol.170.9.4854. J Immunol. 2003. PMID: 12728922 Free article.
79 results