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81 results

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Page 1
Age-Adjusted D-Dimer Cutoff Levels to Rule Out Deep Vein Thrombosis.
Le Gal G, Robert-Ebadi H, Thiruganasambandamoorthy V, Moustafa F, Penaloza A, Catella J, Grenot MC, Visser S, Mazzolai L, Plumacker A, Barco S, Lang E, Tagalakis V, Deroche C, Garnett M, Hulme J, Roy PM, Ghuysen A, Couturaud F, Engelberger R, El Kouri D, Aujesky D, Righini M; ADJUST-DVT Investigators. Le Gal G, et al. JAMA. 2026 Feb 3;335(5):416-424. doi: 10.1001/jama.2025.21561. JAMA. 2026. PMID: 41490105 Clinical Trial.
IMPORTANCE: The age-adjusted D-dimer cutoff (age 10 g/L in patients 50 years or older), safely increases the diagnostic yield of D-dimer in patients with suspected pulmonary embolism but has not been validated in patients with suspected leg deep vein thrombosis …
IMPORTANCE: The age-adjusted D-dimer cutoff (age 10 g/L in patients 50 years or older), safely increases the diagnostic yield of D-dimer in …
Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism.
van der Pol LM, Tromeur C, Bistervels IM, Ni Ainle F, van Bemmel T, Bertoletti L, Couturaud F, van Dooren YPA, Elias A, Faber LM, Hofstee HMA, van der Hulle T, Kruip MJHA, Maignan M, Mairuhu ATA, Middeldorp S, Nijkeuter M, Roy PM, Sanchez O, Schmidt J, Ten Wolde M, Klok FA, Huisman MV; Artemis Study Investigators. van der Pol LM, et al. N Engl J Med. 2019 Mar 21;380(12):1139-1149. doi: 10.1056/NEJMoa1813865. N Engl J Med. 2019. PMID: 30893534 Clinical Trial.
Adaptation of the YEARS algorithm for pregnant women involved compression ultrasonography for women with symptoms of deep-vein thrombosis; if the results were positive (i.e., a clot was present), CT pulmonary angiography was not performed. ...Pulmonary emboli …
Adaptation of the YEARS algorithm for pregnant women involved compression ultrasonography for women with symptoms of deep-vein …
Arthroscopic surgery for degenerative knee disease (osteoarthritis including degenerative meniscal tears).
O'Connor D, Johnston RV, Brignardello-Petersen R, Poolman RW, Cyril S, Vandvik PO, Buchbinder R. O'Connor D, et al. Cochrane Database Syst Rev. 2022 Mar 3;3(3):CD014328. doi: 10.1002/14651858.CD014328. Cochrane Database Syst Rev. 2022. PMID: 35238404 Free PMC article.
We downgraded this evidence to moderate certainty as the 95% confidence interval does not rule in or rule out a clinically important change. After surgery, 74 out of 100 people reported treatment success with placebo and 82 out of 100 people reported treatment succe …
We downgraded this evidence to moderate certainty as the 95% confidence interval does not rule in or rule out a clinically imp …
Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis.
Geersing GJ, Zuithoff NP, Kearon C, Anderson DR, Ten Cate-Hoek AJ, Elf JL, Bates SM, Hoes AW, Kraaijenhagen RA, Oudega R, Schutgens RE, Stevens SM, Woller SC, Wells PS, Moons KG. Geersing GJ, et al. BMJ. 2014 Mar 10;348:g1340. doi: 10.1136/bmj.g1340. BMJ. 2014. PMID: 24615063 Free PMC article. Review.
OBJECTIVE: To assess the accuracy of the Wells rule for excluding deep vein thrombosis and whether this accuracy applies to different subgroups of patients. ...MAIN OUTCOME MEASURES: Multilevel logistic regression models, including an interaction term …
OBJECTIVE: To assess the accuracy of the Wells rule for excluding deep vein thrombosis and whether this accuracy …
A systematic review of clinical prediction scores for deep vein thrombosis.
Kafeza M, Shalhoub J, Salooja N, Bingham L, Spagou K, Davies AH. Kafeza M, et al. Phlebology. 2017 Sep;32(8):516-531. doi: 10.1177/0268355516678729. Epub 2016 Nov 24. Phlebology. 2017. PMID: 27885107 Free article.
Objective Diagnosis of deep vein thrombosis remains a challenging problem. Various clinical prediction rules have been developed in order to improve diagnosis and decision making in relation to deep vein thrombosis. ...The development of …
Objective Diagnosis of deep vein thrombosis remains a challenging problem. Various clinical prediction rules have been …
Clinical decision rules in primary care: necessary investments for sustainable healthcare.
Heerink JS, Oudega R, Hopstaken R, Koffijberg H, Kusters R. Heerink JS, et al. Prim Health Care Res Dev. 2023 May 2;24:e34. doi: 10.1017/S146342362300021X. Prim Health Care Res Dev. 2023. PMID: 37129072 Free PMC article.
However, in daily primary care, the use of CDRs is limited to only a few isolated rules. In this paper, we aimed to provide insight into the laborious path required to implement a viable CDR. At the same time, we noted that the limited use of CDRs in primary …
However, in daily primary care, the use of CDRs is limited to only a few isolated rules. In this paper, we aimed to provide in …
Diagnosing deep vein thrombosis in cancer patients with suspected symptoms: An individual participant data meta-analysis.
Takada T, van Doorn S, Parpia S, de Wit K, Anderson DR, Stevens SM, Woller SC, Ten Cate-Hoek AJ, Elf JL, Kraaijenhagen RA, Schutgens REG, Wells PS, Kearon C, Moons KGM, Geersing GJ. Takada T, et al. J Thromb Haemost. 2020 Sep;18(9):2245-2252. doi: 10.1111/jth.14900. Epub 2020 Jul 8. J Thromb Haemost. 2020. PMID: 32433797 Free article.
BACKGROUND: A previous individual participant data (IPD) meta-analysis showed that the Wells rule and D-dimer testing cannot exclude suspected deep vein thrombosis (DVT) in cancer patients. ...The newly developed rule showed a pooled c-statistic …
BACKGROUND: A previous individual participant data (IPD) meta-analysis showed that the Wells rule and D-dimer testing cannot exclude …
A simplified decision rule to rule out deep vein thrombosis using clinical assessment and D-dimer.
Xu K, de Wit K, Geersing GJ, Takada T, Schutgens R, Elf J, Kearon C, Parpia S. Xu K, et al. J Thromb Haemost. 2021 Jul;19(7):1752-1758. doi: 10.1111/jth.15337. Epub 2021 May 4. J Thromb Haemost. 2021. PMID: 33834620 Free article.
BACKGROUND: Current clinical decision rules to exclude deep vein thrombosis (DVT) are underused partly because of their complexity. A simplified rule that can be easily applied would be more appealing to use in clinical practice. METHODS: We used indiv …
BACKGROUND: Current clinical decision rules to exclude deep vein thrombosis (DVT) are underused partly because of their …
Excluding deep vein thrombosis safely in primary care.
Toll DB, Oudega R, Bulten RJ, Hoes AW, Moons KG. Toll DB, et al. J Fam Pract. 2006 Jul;55(7):613-8. J Fam Pract. 2006. PMID: 16822449
Our validated primary care rule safely excludes deep vein thrombosis in one-quarter of patients suspected of having the disease. We recommend the use of this rule by family practitioners....
Our validated primary care rule safely excludes deep vein thrombosis in one-quarter of patients su …
Accuracy of the Wells Rule in diagnosing deep vein thrombosis in primary health care.
Tagelag M, Elley CR. Tagelag M, et al. N Z Med J. 2007 Sep 7;120(1261):U2705. N Z Med J. 2007. PMID: 17853927
AIM: A clinical decision rule to aid in the diagnosis of deep vein thrombosis (DVT) was derived by Wells and has been validated in several secondary care settings. ...The aim of this study was to assess the accuracy of the Wells Rule in N …
AIM: A clinical decision rule to aid in the diagnosis of deep vein thrombosis (DVT) was derived by Wells and has …
81 results