Principe DR - Search Results

1

HAI-1 is an independent predictor of lung cancer mortality and is required for M1 macrophage polarization.

Borowicz S, Principe DR, Dorman MJ, McHenry AJ, Sondarva G, Kumar S, Ananthanarayanan V, Simms PE, Hess A, Rana A. Borowicz S, et al. Among authors: principe dr. PLoS One. 2021 Jun 29;16(6):e0252197. doi: 10.1371/journal.pone.0252197. eCollection 2021. PLoS One. 2021. PMID: 34185790 Free PMC article.

2

KRAS^G12D and TP53^R167H Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs.

Principe DR, Overgaard NH, Park AJ, Diaz AM, Torres C, McKinney R, Dorman MJ, Castellanos K, Schwind R, Dawson DW, Rana A, Maker A, Munshi HG, Rund LA, Grippo PJ, Schook LB. Principe DR, et al. Sci Rep. 2018 Aug 22;8(1):12548. doi: 10.1038/s41598-018-30916-6. Sci Rep. 2018. PMID: 30135483 Free PMC article.

3

TGFβ Blockade Augments PD-1 Inhibition to Promote T-Cell-Mediated Regression of Pancreatic Cancer.

Principe DR, Park A, Dorman MJ, Kumar S, Viswakarma N, Rubin J, Torres C, McKinney R, Munshi HG, Grippo PJ, Rana A. Principe DR, et al. Mol Cancer Ther. 2019 Mar;18(3):613-620. doi: 10.1158/1535-7163.MCT-18-0850. Epub 2018 Dec 26. Mol Cancer Ther. 2019. PMID: 30587556 Free PMC article.

4

p110γ deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity.

Torres C, Mancinelli G, Cordoba-Chacon J, Viswakarma N, Castellanos K, Grimaldo S, Kumar S, Principe D, Dorman MJ, McKinney R, Hirsch E, Dawson D, Munshi HG, Rana A, Grippo PJ. Torres C, et al. Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14724-14733. doi: 10.1073/pnas.1813012116. Epub 2019 Jul 2. Proc Natl Acad Sci U S A. 2019. PMID: 31266893 Free PMC article.

5

Combined radio-immunotherapy leads to complete clinical regression of stage IV Merkel cell carcinoma.

Principe DR, Clark JI, Emami B, Borowicz S. Principe DR, et al. BMJ Case Rep. 2019 Aug 21;12(8):e230518. doi: 10.1136/bcr-2019-230518. BMJ Case Rep. 2019. PMID: 31439556 Free PMC article.

6

Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer.

Kumar S, Principe DR, Singh SK, Viswakarma N, Sondarva G, Rana B, Rana A. Kumar S, et al. Among authors: principe dr. Pharmaceuticals (Basel). 2020 Jan 7;13(1):9. doi: 10.3390/ph13010009. Pharmaceuticals (Basel). 2020. PMID: 31936067 Free PMC article. Review.

7

Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy.

Principe DR, Narbutis M, Kumar S, Park A, Viswakarma N, Dorman MJ, Kamath SD, Grippo PJ, Fishel ML, Hwang RF, Thummuri D, Underwood PW, Munshi HG, Trevino JG, Rana A. Principe DR, et al. Cancer Res. 2020 Aug 1;80(15):3101-3115. doi: 10.1158/0008-5472.CAN-19-2959. Epub 2020 Apr 1. Cancer Res. 2020. PMID: 32238357 Free PMC article.

8

Updated risk factors to inform early pancreatic cancer screening and identify high risk patients.

Principe DR, Rana A. Principe DR, et al. Cancer Lett. 2020 Aug 10;485:56-65. doi: 10.1016/j.canlet.2020.04.022. Epub 2020 May 8. Cancer Lett. 2020. PMID: 32389710 Free PMC article.

9

Frequency and prognostic value of mutations associated with the homologous recombination DNA repair pathway in a large pan cancer cohort.

Principe DR, Narbutis M, Koch R, Rana A. Principe DR, et al. Sci Rep. 2020 Nov 19;10(1):20223. doi: 10.1038/s41598-020-76975-6. Sci Rep. 2020. PMID: 33214570 Free PMC article.

10

Trials and tribulations of pancreatic cancer immunotherapy.

Principe DR, Korc M, Kamath SD, Munshi HG, Rana A. Principe DR, et al. Cancer Lett. 2021 Apr 28;504:1-14. doi: 10.1016/j.canlet.2021.01.031. Epub 2021 Feb 4. Cancer Lett. 2021. PMID: 33549709 Free PMC article. Review.

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