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Prior opioid exposure influences parents' sharing of their children's CYP2D6 research results.
Myers MF, Zhang X, McLaughlin B, Kissell D, Perry CL, Veerkamp M, Zhang K, Holm IA, Prows CA. Myers MF, et al. Pharmacogenomics. 2017 Aug;18(13):1199-1213. doi: 10.2217/pgs-2017-0091. Epub 2017 Jul 26. Pharmacogenomics. 2017. PMID: 28745549 Free PMC article.
AIM: To determine parents' use of their children's CYP2D6 research result. We hypothesized that perceived utility, likelihood of sharing and actual sharing of results would differ between parents with children previously exposed (cases) or unexposed (controls …
AIM: To determine parents' use of their children's CYP2D6 research result. We hypothesized that perceived utility, likelihood …
Cross-Generational THC Exposure Alters Heroin Reinforcement in Adult Male Offspring.
Hempel BJ, Crissman ME, Imanalieva A, Melkumyan M, Weiss TD, Winston CA, Riley AL. Hempel BJ, et al. Drug Alcohol Depend. 2020 Jul 1;212:107985. doi: 10.1016/j.drugalcdep.2020.107985. Epub 2020 Apr 25. Drug Alcohol Depend. 2020. PMID: 32386920
BACKGROUND: An emerging area of preclinical research has investigated whether drug use in parents prior to conception influences drug responsivity in their offspring. ...CONCLUSIONS: The present data indicate that parental THC exposure alters th …
BACKGROUND: An emerging area of preclinical research has investigated whether drug use in parents prior to conception influ
Paternal morphine self-administration produces object recognition memory deficits in female, but not male offspring.
Ellis AS, Toussaint AB, Knouse MC, Thomas AS, Bongiovanni AR, Mayberry HL, Bhakta S, Peer K, Bangasser DA, Wimmer ME. Ellis AS, et al. Psychopharmacology (Berl). 2020 Apr;237(4):1209-1221. doi: 10.1007/s00213-019-05450-6. Epub 2020 Jan 7. Psychopharmacology (Berl). 2020. PMID: 31912193 Free PMC article.
RATIONALE: Parental drug use around or before conception can have adverse consequences for offspring. Historically, this research has focused on the effects of maternal substance use on future generations but less is known about the influence of the paternal lineage …
RATIONALE: Parental drug use around or before conception can have adverse consequences for offspring. Historically, this research has …
Effect of morphine exposure on novel object memory of the offspring: The role of histone H3 and ΔFosB.
Sadat-Shirazi MS, Asgari P, Mahboubi S, Nouri Zadeh-Tehrani S, Ashabi G, Rohbani K, Sabzevari S, Soltani H, Khalifeh S, Zarrindast MR. Sadat-Shirazi MS, et al. Brain Res Bull. 2020 Mar;156:141-149. doi: 10.1016/j.brainresbull.2020.01.011. Epub 2020 Jan 17. Brain Res Bull. 2020. PMID: 31958477
It has been demonstrated that alteration in histone acetylation in the regions of the brain involved in the reward which may have an important role in morphine addiction. It is well established that epigenetic changes prior to birth influence the function and develo …
It has been demonstrated that alteration in histone acetylation in the regions of the brain involved in the reward which may have an importa …
Risks and realities: dyadic interaction between 6-month-old infants and their mothers in opioid maintenance treatment.
Sarfi M, Smith L, Waal H, Sundet JM. Sarfi M, et al. Infant Behav Dev. 2011 Dec;34(4):578-89. doi: 10.1016/j.infbeh.2011.06.006. Epub 2011 Aug 7. Infant Behav Dev. 2011. PMID: 21824659
The importance of group membership (exposed versus non-exposed), was reduced when controlling for maternal drug use prior to opioid maintenance treatment (OMT), maternal depression and parenting stress as well as infants' developmental status and sensory-inte …
The importance of group membership (exposed versus non-exposed), was reduced when controlling for maternal drug use prior to opioi