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Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of multiple sclerosis-directed therapeutics.
Evangelidou M, Karamita M, Vamvakas SS, Szymkowski DE, Probert L. Evangelidou M, et al. Among authors: probert l. J Immunol. 2014 May 1;192(9):4122-33. doi: 10.4049/jimmunol.1300633. Epub 2014 Mar 28. J Immunol. 2014. PMID: 24683189
A Cyclic Altered Peptide Analogue Based on Myelin Basic Protein 87-99 Provides Lasting Prophylactic and Therapeutic Protection Against Acute Experimental Autoimmune Encephalomyelitis.
Emmanouil M, Tseveleki V, Triantafyllakou I, Nteli A, Tselios T, Probert L. Emmanouil M, et al. Among authors: probert l. Molecules. 2018 Jan 31;23(2):304. doi: 10.3390/molecules23020304. Molecules. 2018. PMID: 29385090 Free PMC article.
Mesenchymal Stem Cell Protection of Neurons against Glutamate Excitotoxicity Involves Reduction of NMDA-Triggered Calcium Responses and Surface GluR1, and Is Partly Mediated by TNF.
Papazian I, Kyrargyri V, Evangelidou M, Voulgari-Kokota A, Probert L. Papazian I, et al. Among authors: probert l. Int J Mol Sci. 2018 Feb 25;19(3):651. doi: 10.3390/ijms19030651. Int J Mol Sci. 2018. PMID: 29495345 Free PMC article.
TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury.
Taoufik E, Petit E, Divoux D, Tseveleki V, Mengozzi M, Roberts ML, Valable S, Ghezzi P, Quackenbush J, Brines M, Cerami A, Probert L. Taoufik E, et al. Among authors: probert l. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6185-90. doi: 10.1073/pnas.0801447105. Epub 2008 Apr 14. Proc Natl Acad Sci U S A. 2008. PMID: 18413601 Free PMC article.
Ischemic neuronal damage.
Taoufik E, Probert L. Taoufik E, et al. Among authors: probert l. Curr Pharm Des. 2008;14(33):3565-73. doi: 10.2174/138161208786848748. Curr Pharm Des. 2008. PMID: 19075733 Review.
Inhibition of the neuronal NFκB pathway attenuates bortezomib-induced neuropathy in a mouse model.
Alé A, Bruna J, Calls A, Karamita M, Haralambous S, Probert L, Navarro X, Udina E. Alé A, et al. Among authors: probert l. Neurotoxicology. 2016 Jul;55:58-64. doi: 10.1016/j.neuro.2016.05.004. Epub 2016 May 19. Neurotoxicology. 2016. PMID: 27211850
Differential contributions of microglial and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice.
Kyrargyri V, Vega-Flores G, Gruart A, Delgado-García JM, Probert L. Kyrargyri V, et al. Among authors: probert l. Glia. 2015 Apr;63(4):549-66. doi: 10.1002/glia.22756. Epub 2014 Oct 9. Glia. 2015. PMID: 25297800
Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB.
Taoufik E, Tseveleki V, Chu SY, Tselios T, Karin M, Lassmann H, Szymkowski DE, Probert L. Taoufik E, et al. Among authors: probert l. Brain. 2011 Sep;134(Pt 9):2722-35. doi: 10.1093/brain/awr203. Brain. 2011. PMID: 21908876
A role for neuronal NF-κB in suppressing neuroinflammation and promoting neuroprotection in the CNS.
Emmanouil M, Taoufik E, Tseveleki V, Vamvakas SS, Probert L. Emmanouil M, et al. Among authors: probert l. Adv Exp Med Biol. 2011;691:575-81. doi: 10.1007/978-1-4419-6612-4_60. Adv Exp Med Biol. 2011. PMID: 21153363 No abstract available.
Comparative gene expression analysis in mouse models for multiple sclerosis, Alzheimer's disease and stroke for identifying commonly regulated and disease-specific gene changes.
Tseveleki V, Rubio R, Vamvakas SS, White J, Taoufik E, Petit E, Quackenbush J, Probert L. Tseveleki V, et al. Among authors: probert l. Genomics. 2010 Aug;96(2):82-91. doi: 10.1016/j.ygeno.2010.04.004. Epub 2010 May 7. Genomics. 2010. PMID: 20435134 Free PMC article.
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