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InsP7 is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics.
Sahu S, Wang Z, Jiao X, Gu C, Jork N, Wittwer C, Li X, Hostachy S, Fiedler D, Wang H, Jessen HJ, Kiledjian M, Shears SB. Sahu S, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:201922284. doi: 10.1073/pnas.1922284117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727897
Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination.
He Y, Ren J, Xu X, Ni K, Schwader A, Finney R, Wang C, Sun L, Klarmann K, Keller J, Tubbs A, Nussenzweig A, Muegge K. He Y, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:202004112. doi: 10.1073/pnas.2004112117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727902
Ancestral roles of atypical cadherins in planar cell polarity.
Brooun M, Klimovich A, Bashkurov M, Pearson BJ, Steele RE, McNeill H. Brooun M, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:201917570. doi: 10.1073/pnas.1917570117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727892
An ErbB2 splice variant lacking exon 16 drives lung carcinoma.
Smith HW, Yang L, Ling C, Walsh A, Martinez VD, Boucher J, Zuo D, Sokol ES, Pavlick DC, Frampton GM, Chmielecki J, Jones LM, Roux PP, Lockwood WW, Muller WJ. Smith HW, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:202007474. doi: 10.1073/pnas.2007474117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727899
Rational design to control the trade-off between receptor affinity and cooperativity.
Ortega G, Mariottini D, Troina A, Dahlquist FW, Ricci F, Plaxco KW. Ortega G, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:202006254. doi: 10.1073/pnas.2006254117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727893
LRCH1 deficiency enhances LAT signalosome formation and CD8+ T cell responses against tumors and pathogens.
Liu C, Xu X, Han L, Wan X, Zheng L, Li C, Liao Z, Xiao J, Zhong R, Zheng X, Wang Q, Li Z, Chen H, Wei B, Wang H. Liu C, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:202000970. doi: 10.1073/pnas.2000970117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727906
Timing social distancing to avert unmanageable COVID-19 hospital surges.
Duque D, Morton DP, Singh B, Du Z, Pasco R, Meyers LA. Duque D, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:202009033. doi: 10.1073/pnas.2009033117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727898
Popular repugnance contrasts with legal bans on controversial markets.
Roth AE, Wang SW. Roth AE, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:202005828. doi: 10.1073/pnas.2005828117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727903
Single-cell RNA-seq analysis revealed long-lasting adverse effects of tamoxifen on neurogenesis in prenatal and adult brains.
Lee CM, Zhou L, Liu J, Shi J, Geng Y, Liu M, Wang J, Su X, Barad N, Wang J, Sun YE, Lin Q. Lee CM, et al. Proc Natl Acad Sci U S A. 2020 Jul 29:201918883. doi: 10.1073/pnas.1918883117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 32727894
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