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Computational design of a protein-based enzyme inhibitor.
Procko E, Hedman R, Hamilton K, Seetharaman J, Fleishman SJ, Su M, Aramini J, Kornhaber G, Hunt JF, Tong L, Montelione GT, Baker D. Procko E, et al. J Mol Biol. 2013 Sep 23;425(18):3563-75. doi: 10.1016/j.jmb.2013.06.035. Epub 2013 Jul 1. J Mol Biol. 2013. PMID: 23827138 Free PMC article.
Intracellular delivery system for antibody-Peptide drug conjugates.
Berguig GY, Convertine AJ, Frayo S, Kern HB, Procko E, Roy D, Srinivasan S, Margineantu DH, Booth G, Palanca-Wessels MC, Baker D, Hockenbery D, Press OW, Stayton PS. Berguig GY, et al. Among authors: procko e. Mol Ther. 2015 May;23(5):907-917. doi: 10.1038/mt.2015.22. Epub 2015 Feb 11. Mol Ther. 2015. PMID: 25669432 Free PMC article.
Motif-Driven Design of Protein-Protein Interfaces.
Silva DA, Correia BE, Procko E. Silva DA, et al. Among authors: procko e. Methods Mol Biol. 2016;1414:285-304. doi: 10.1007/978-1-4939-3569-7_17. Methods Mol Biol. 2016. PMID: 27094298
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.
Berger S, Procko E, Margineantu D, Lee EF, Shen BW, Zelter A, Silva DA, Chawla K, Herold MJ, Garnier JM, Johnson R, MacCoss MJ, Lessene G, Davis TN, Stayton PS, Stoddard BL, Fairlie WD, Hockenbery DM, Baker D. Berger S, et al. Among authors: procko e. Elife. 2016 Nov 2;5:e20352. doi: 10.7554/eLife.20352. Elife. 2016. PMID: 27805565 Free PMC article.
Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants.
Zhang L, Dutta S, Xiong S, Chan M, Chan KK, Fan TM, Bailey KL, Lindeblad M, Cooper LM, Rong L, Gugliuzza AF, Shukla D, Procko E, Rehman J, Malik AB. Zhang L, et al. Among authors: procko e. Nat Chem Biol. 2022 Mar;18(3):342-351. doi: 10.1038/s41589-021-00965-6. Epub 2022 Jan 19. Nat Chem Biol. 2022. PMID: 35046611 Free PMC article.
54 results