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A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS.
Sinha S, Subramanian S, Proctor TM, Kaler LJ, Grafe M, Dahan R, Huan J, Vandenbark AA, Burrows GG, Offner H. Sinha S, et al. Among authors: proctor tm. J Neurosci. 2007 Nov 14;27(46):12531-9. doi: 10.1523/JNEUROSCI.3599-07.2007. J Neurosci. 2007. PMID: 18003831 Free PMC article.
Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis.
Sinha S, Miller L, Subramanian S, McCarty OJ, Proctor T, Meza-Romero R, Huan J, Burrows GG, Vandenbark AA, Offner H. Sinha S, et al. J Neuroimmunol. 2010 Aug 25;225(1-2):52-61. doi: 10.1016/j.jneuroim.2010.04.013. Epub 2010 May 23. J Neuroimmunol. 2010. PMID: 20546940 Free PMC article.
Coordinate control of axon defasciculation and myelination by laminin-2 and -8.
Yang D, Bierman J, Tarumi YS, Zhong YP, Rangwala R, Proctor TM, Miyagoe-Suzuki Y, Takeda S, Miner JH, Sherman LS, Gold BG, Patton BL. Yang D, et al. Among authors: proctor tm. J Cell Biol. 2005 Feb 14;168(4):655-66. doi: 10.1083/jcb.200411158. Epub 2005 Feb 7. J Cell Biol. 2005. PMID: 15699217 Free PMC article.
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