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Page 1
Regional heterogeneity of the blood-brain barrier.
Blanchette M, Bajc K, Gastfriend BD, Profaci CP, Ruderisch N, Dorrier CE, Zhong G, Cuevas-Diaz Duran R, Harvey SS, Garcia-Pak IH, Pintarić L, Leclerc M, Reveret L, Émond V, Wang A, Pant D, Tsai LT, Calon F, Isoherranen N, Palecek SP, Shusta EV, Wu J, Daneman R. Blanchette M, et al. Among authors: profaci cp. Nat Commun. 2025 Aug 8;16(1):7332. doi: 10.1038/s41467-025-61841-8. Nat Commun. 2025. PMID: 40781224 Free PMC article.
Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism.
Profaci CP, Harvey SS, Bajc K, Zhang TZ, Jeffrey DA, Zhang AZ, Nemec KM, Davtyan H, O'Brien CA, McKinsey GL, Longworth A, McMullen TP, Capocchi JK, Gonzalez JG, Lawson DA, Arnold TD, Davalos D, Blurton-Jones M, Dabertrand F, Bennett FC, Daneman R. Profaci CP, et al. Neuron. 2024 Sep 4;112(17):2910-2921.e7. doi: 10.1016/j.neuron.2024.07.015. Epub 2024 Aug 13. Neuron. 2024. PMID: 39142282 Free PMC article.
Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege.
Ma Y, Sannino D, Linden JR, Haigh S, Zhao B, Grigg JB, Zumbo P, Dündar F, Butler D, Profaci CP, Telesford K, Winokur PN, Rumah KR, Gauthier SA, Fischetti VA, McClane BA, Uzal FA, Zexter L, Mazzucco M, Rudick R, Danko D, Balmuth E, Nealon N, Perumal J, Kaunzner U, Brito IL, Chen Z, Xiang JZ, Betel D, Daneman R, Sonnenberg GF, Mason CE, Vartanian T. Ma Y, et al. Among authors: profaci cp. J Clin Invest. 2023 May 1;133(9):e163239. doi: 10.1172/JCI163239. J Clin Invest. 2023. PMID: 36853799 Free PMC article.
Lessons from the Stories of Women in Neuroscience.
Sibener LJ, Kirchgessner MA, Steiner S, Santiago C, Cassataro D, Rossa M, Profaci CP, Padilla-Coreano N. Sibener LJ, et al. Among authors: profaci cp. J Neurosci. 2022 Jun 15;42(24):4769-4773. doi: 10.1523/JNEUROSCI.0536-22.2022. J Neurosci. 2022. PMID: 35705494 Free PMC article.
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders.
Martin M, Vermeiren S, Bostaille N, Eubelen M, Spitzer D, Vermeersch M, Profaci CP, Pozuelo E, Toussay X, Raman-Nair J, Tebabi P, America M, De Groote A, Sanderson LE, Cabochette P, Germano RFV, Torres D, Boutry S, de Kerchove d'Exaerde A, Bellefroid EJ, Phoenix TN, Devraj K, Lacoste B, Daneman R, Liebner S, Vanhollebeke B. Martin M, et al. Among authors: profaci cp. Science. 2022 Feb 18;375(6582):eabm4459. doi: 10.1126/science.abm4459. Epub 2022 Feb 18. Science. 2022. PMID: 35175798
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes.
Pulido RS, Munji RN, Chan TC, Quirk CR, Weiner GA, Weger BD, Rossi MJ, Elmsaouri S, Malfavon M, Deng A, Profaci CP, Blanchette M, Qian T, Foreman KL, Shusta EV, Gorman MR, Gachon F, Leutgeb S, Daneman R. Pulido RS, et al. Among authors: profaci cp. Neuron. 2020 Dec 9;108(5):937-952.e7. doi: 10.1016/j.neuron.2020.09.002. Epub 2020 Sep 25. Neuron. 2020. PMID: 32979312 Free PMC article.
12 results