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The proline-rich P65 protein of Mycoplasma pneumoniae is a component of the Triton X-100-insoluble fraction and exhibits size polymorphism in the strains M129 and FH.
Proft T, Hilbert H, Layh-Schmitt G, Herrmann R. Proft T, et al. J Bacteriol. 1995 Jun;177(12):3370-8. doi: 10.1128/jb.177.12.3370-3378.1995. J Bacteriol. 1995. PMID: 7768845 Free PMC article.
Previously, we described the identification of a novel Mycoplasma pneumoniae M129 protein, named P65 because of its apparent molecular mass of 65 kDa estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (T. Proft and R. Herrmann, Mol. Microbiol. 13 …
Previously, we described the identification of a novel Mycoplasma pneumoniae M129 protein, named P65 because of its apparent molecular mass …
Transposon mutagenesis reinforces the correlation between Mycoplasma pneumoniae cytoskeletal protein HMW2 and cytadherence.
Krause DC, Proft T, Hedreyda CT, Hilbert H, Plagens H, Herrmann R. Krause DC, et al. J Bacteriol. 1997 Apr;179(8):2668-77. doi: 10.1128/jb.179.8.2668-2677.1997. J Bacteriol. 1997. PMID: 9098066 Free PMC article.
The laminin-binding protein Lbp from Streptococcus pyogenes is a zinc receptor.
Linke C, Caradoc-Davies TT, Young PG, Proft T, Baker EN. Linke C, et al. J Bacteriol. 2009 Sep;191(18):5814-23. doi: 10.1128/JB.00485-09. Epub 2009 Jul 17. J Bacteriol. 2009. PMID: 19617361 Free PMC article.
The bacterial superantigen streptococcal mitogenic exotoxin Z is the major immunoactive agent of Streptococcus pyogenes.
Unnikrishnan M, Altmann DM, Proft T, Wahid F, Cohen J, Fraser JD, Sriskandan S. Unnikrishnan M, et al. J Immunol. 2002 Sep 1;169(5):2561-9. doi: 10.4049/jimmunol.169.5.2561. J Immunol. 2002. PMID: 12193726
Human Vbeta8(+) T cell proliferation in response to S. pyogenes was SMEZ-dependent. Cells from HLA-DQ8 transgenic mice were 3 logs more sensitive to SMEZ-13 than cells from HLA-DR1 transgenic or wild-type mice. In the mouse, SMEZ targeted the human Vbeta8(+) TCR homologue, …
Human Vbeta8(+) T cell proliferation in response to S. pyogenes was SMEZ-dependent. Cells from HLA-DQ8 transgenic mice were 3 logs mo …
Streptococcal superantigens: categorization and clinical associations.
Commons RJ, Smeesters PR, Proft T, Fraser JD, Robins-Browne R, Curtis N. Commons RJ, et al. Trends Mol Med. 2014 Jan;20(1):48-62. doi: 10.1016/j.molmed.2013.10.004. Epub 2013 Nov 6. Trends Mol Med. 2014. PMID: 24210845 Review.
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