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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1936 1
1937 3
1938 6
1939 2
1940 1
1941 2
1942 3
1943 1
1944 4
1945 8
1946 33
1947 39
1948 60
1949 47
1950 108
1951 145
1952 172
1953 155
1954 157
1955 152
1956 162
1957 210
1958 195
1959 213
1960 263
1961 273
1962 352
1963 535
1964 653
1965 522
1966 576
1967 808
1968 891
1969 1063
1970 1115
1971 1150
1972 1264
1973 1382
1974 1589
1975 1666
1976 1524
1977 1551
1978 1517
1979 1776
1980 1868
1981 1865
1982 1902
1983 1968
1984 2106
1985 2137
1986 2095
1987 2117
1988 2213
1989 2320
1990 2292
1991 2269
1992 2259
1993 2232
1994 2177
1995 2234
1996 2217
1997 2183
1998 2226
1999 2198
2000 2445
2001 2425
2002 2521
2003 2418
2004 2401
2005 2658
2006 2790
2007 2692
2008 2995
2009 3004
2010 3170
2011 3289
2012 3474
2013 3467
2014 3480
2015 3442
2016 3325
2017 3353
2018 3418
2019 3360
2020 3639
2021 3550
2022 3243
2023 3082
2024 3180
2025 3521
2026 2099

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137,973 results

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Page 1
Progesterone and abnormal uterine bleeding/menstrual disorders.
Jewson M, Purohit P, Lumsden MA. Jewson M, et al. Best Pract Res Clin Obstet Gynaecol. 2020 Nov;69:62-73. doi: 10.1016/j.bpobgyn.2020.05.004. Epub 2020 Jun 5. Best Pract Res Clin Obstet Gynaecol. 2020. PMID: 32698992 Review.
In menopausal women, progesterones and progestogens prevent endometrial hyperplasia and aim to reduce the development of endometrial cancer. We hope to make clear current best practice including preparation, specific benefits and risks. Progesterone also acts in con …
In menopausal women, progesterones and progestogens prevent endometrial hyperplasia and aim to reduce the development of endometrial …
Progesterone modulates neuronal excitability bidirectionally.
Kapur J, Joshi S. Kapur J, et al. Neurosci Lett. 2021 Jan 23;744:135619. doi: 10.1016/j.neulet.2020.135619. Epub 2021 Jan 6. Neurosci Lett. 2021. PMID: 33421486 Free PMC article. Review.
There is emerging evidence that progesterone exerts excitatory effects by activating its cognate receptors (progesterone receptors, PRs) through enhanced expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs). ...Here, we review …
There is emerging evidence that progesterone exerts excitatory effects by activating its cognate receptors (progesterone recep …
Progesterone, reproduction, and psychiatric illness.
Standeven LR, McEvoy KO, Osborne LM. Standeven LR, et al. Best Pract Res Clin Obstet Gynaecol. 2020 Nov;69:108-126. doi: 10.1016/j.bpobgyn.2020.06.001. Epub 2020 Jun 18. Best Pract Res Clin Obstet Gynaecol. 2020. PMID: 32723604 Free PMC article. Review.
This chapter presents evidence of the role of endogenous progesterone and its metabolites in such mood symptoms, and then goes on to cover the evidence concerning exogenous progesterone's effects on mood. Overall, the literature does not support an associatio …
This chapter presents evidence of the role of endogenous progesterone and its metabolites in such mood symptoms, and then goes on to …
Progesterone and neuroprotection.
Singh M, Su C. Singh M, et al. Horm Behav. 2013 Feb;63(2):284-90. doi: 10.1016/j.yhbeh.2012.06.003. Epub 2012 Jun 23. Horm Behav. 2013. PMID: 22732134 Free PMC article. Review.
In fact, progesterone has been shown to exert neuroprotective effects, both in cell models, animal models and in humans. ...We also discuss the receptor pharmacology of progesterone's neuroprotective effects and present a conceptual model of progesterone …
In fact, progesterone has been shown to exert neuroprotective effects, both in cell models, animal models and in humans. ...We also d …
Progesterone for the prevention and treatment of osteoporosis in women.
Prior JC. Prior JC. Climacteric. 2018 Aug;21(4):366-374. doi: 10.1080/13697137.2018.1467400. Epub 2018 Jul 2. Climacteric. 2018. PMID: 29962257 Free article. Review.
Progesterone plus estradiol or other antiresorptive therapies adds 0.68%/year and may be a highly effective osteoporosis treatment. Randomized controlled trials are still needed to confirm progesterone's important role in women's bone formation....
Progesterone plus estradiol or other antiresorptive therapies adds 0.68%/year and may be a highly effective osteoporosis treatment. R …
Progesterone withdrawal: key to parturition.
Zakar T, Hertelendy F. Zakar T, et al. Am J Obstet Gynecol. 2007 Apr;196(4):289-96. doi: 10.1016/j.ajog.2006.09.005. Am J Obstet Gynecol. 2007. PMID: 17403397 Review.
Whereas the essential role of progesterone in the maintenance of pregnancy is accepted generally, the mechanisms that suppress progesterone's function near term to allow labor and delivery of the conceptus are still shrouded in uncertainty. In most subprimate …
Whereas the essential role of progesterone in the maintenance of pregnancy is accepted generally, the mechanisms that suppress pro …
Progesterone-mediated immunomodulation in ruminant early pregnancy: mechanisms and implications for bovine fertility.
Batool I, Kausar R, Qamar MS. Batool I, et al. Vet Res Commun. 2025 Nov 4;50(1):21. doi: 10.1007/s11259-025-10963-x. Vet Res Commun. 2025. PMID: 41186651 Review.
These include genomic pathways involving nuclear progesterone receptors, non-genomic signaling through membrane progesterone receptors and progesterone receptor membrane component 1, and immunoregulatory effects mediated by the progesterone-induced blo …
These include genomic pathways involving nuclear progesterone receptors, non-genomic signaling through membrane progesterone r …
Progesterone, brain-derived neurotrophic factor and neuroprotection.
Singh M, Su C. Singh M, et al. Neuroscience. 2013 Jun 3;239:84-91. doi: 10.1016/j.neuroscience.2012.09.056. Epub 2012 Oct 2. Neuroscience. 2013. PMID: 23036620 Free PMC article. Review.
In addition, progesterone has well-described protective effects against numerous insults in a variety of cell models, animal models and in humans. ...Among the key mediators of progesterone's beneficial effects is the family of growth factors called neurotrop …
In addition, progesterone has well-described protective effects against numerous insults in a variety of cell models, animal models a …
Progesterone: therapeutic opportunities for neuroprotection and myelin repair.
Schumacher M, Guennoun R, Stein DG, De Nicola AF. Schumacher M, et al. Pharmacol Ther. 2007 Oct;116(1):77-106. doi: 10.1016/j.pharmthera.2007.06.001. Epub 2007 Jun 18. Pharmacol Ther. 2007. PMID: 17659348 Review.
Progesterone and its metabolites promote the viability of neurons in the brain and spinal cord. Their neuroprotective effects have been documented in different lesion models, including traumatic brain injury (TBI), experimentally induced ischemia, spinal cord lesions and a …
Progesterone and its metabolites promote the viability of neurons in the brain and spinal cord. Their neuroprotective effects have be …
Progesterone, 5a-dihydropogesterone and allopregnanolone's effects on seizures: A review of animal and clinical studies.
Wu YV, Burnham WM. Wu YV, et al. Seizure. 2018 Dec;63:26-36. doi: 10.1016/j.seizure.2018.10.012. Epub 2018 Oct 28. Seizure. 2018. PMID: 30391663 Free article. Review.
Progesterone and ALLO have also shown anti-seizure effects in clinical trials. A large Phase III trial has revealed that female patients with premenstrual exacerbations of seizures benefit most from progesterone therapy. ...ALLO's C3 methyl analog ganaxolone is unde …
Progesterone and ALLO have also shown anti-seizure effects in clinical trials. A large Phase III trial has revealed that female patie …
137,973 results
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