Molecular overview of progressive familial intrahepatic cholestasis.
Amirneni S, Haep N, Gad MA, Soto-Gutierrez A, Squires JE, Florentino RM.
Amirneni S, et al.
World J Gastroenterol. 2020 Dec 21;26(47):7470-7484. doi: 10.3748/wjg.v26.i47.7470.
World J Gastroenterol. 2020.
PMID: 33384548
Free PMC article.
Review.
This condition could be caused by defects of the hepatocytes, which are responsible for the complex process of bile formation and secretion, and/or caused by defects in the secretory machinery of cholangiocytes. Several mutations and pathways that lead to cholestasis have …
This condition could be caused by defects of the hepatocytes, which are responsible for the complex process of bile formation and secretion, …