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Recent advances in tissue (pro)renin imaging.
Prokai A, Peti-Peterdi J. Prokai A, et al. Front Biosci (Elite Ed). 2010 Jun 1;2:1227-33. doi: 10.2741/e182. Front Biosci (Elite Ed). 2010. PMID: 20515794 Free PMC article. Review.
Also, the newly discovered (pro)renin receptor is a new element of the ever broadening renin-angiotensin system (RAS). The complexity of RAS including the recently recognized collecting duct site of (pro)renin (a term denoting both renin and prorenin) synthesis requ …
Also, the newly discovered (pro)renin receptor is a new element of the ever broadening renin-angiotensin system (RAS). The complexity …
The macula densa prorenin receptor is essential in renin release and blood pressure control.
Riquier-Brison ADM, Sipos A, Prókai Á, Vargas SL, Toma L, Meer EJ, Villanueva KG, Chen JCM, Gyarmati G, Yih C, Tang E, Nadim B, Pendekanti S, Garrelds IM, Nguyen G, Danser AHJ, Peti-Peterdi J. Riquier-Brison ADM, et al. Among authors: prokai a. Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F521-F534. doi: 10.1152/ajprenal.00029.2018. Epub 2018 Apr 18. Am J Physiol Renal Physiol. 2018. PMID: 29667908 Free PMC article.
Calcineurin-inhibition Results in Upregulation of Local Renin and Subsequent Vascular Endothelial Growth Factor Production in Renal Collecting Ducts.
Prókai Á, Csohány R, Sziksz E, Pap D, Balicza-Himer L, Boros S, Magda B, Vannay Á, Kis-Petik K, Fekete A, Peti-Peterdi J, Szabó AJ. Prókai Á, et al. Transplantation. 2016 Feb;100(2):325-333. doi: 10.1097/TP.0000000000000961. Transplantation. 2016. PMID: 26502369 Free PMC article.
Visualization of Calcium Dynamics in Kidney Proximal Tubules.
Szebényi K, Füredi A, Kolacsek O, Csohány R, Prókai Á, Kis-Petik K, Szabó A, Bősze Z, Bender B, Tóvári J, Enyedi Á, Orbán TI, Apáti Á, Sarkadi B. Szebényi K, et al. Among authors: prokai a. J Am Soc Nephrol. 2015 Nov;26(11):2731-40. doi: 10.1681/ASN.2014070705. Epub 2015 Mar 18. J Am Soc Nephrol. 2015. PMID: 25788535 Free PMC article.
Sex differences in renin response and changes of capillary diameters after renal ischemia/reperfusion injury.
Csohány R, Prókai Á, Sziksz E, Balicza-Himer L, Pap D, Kosik A, Sugár D, Vannay Á, Kis-Petik K, Fekete A, Szabó AJ. Csohány R, et al. Among authors: prokai a. Pediatr Transplant. 2016 Aug;20(5):619-26. doi: 10.1111/petr.12712. Epub 2016 Apr 19. Pediatr Transplant. 2016. PMID: 27090360
Na+,K+-ATPase is modulated by angiotensin II in diabetic rat kidney--another reason for diabetic nephropathy?
Fekete A, Rosta K, Wagner L, Prokai A, Degrell P, Ruzicska E, Vegh E, Toth M, Ronai K, Rusai K, Somogyi A, Tulassay T, Szabo AJ, Ver A. Fekete A, et al. J Physiol. 2008 Nov 15;586(22):5337-48. doi: 10.1113/jphysiol.2008.156703. Epub 2008 Sep 25. J Physiol. 2008. PMID: 18818245 Free PMC article.
Angiotensin II (ANGII) plays a central role in the enhanced sodium reabsorption in early type 1 diabetes in man and in streptozotocin-induced (STZ) diabetic rats. ...After 7 weeks of STZ-diabetes (i.v. 65 mg kg(-1)) a subgroup of control (C) and diabetic (D7) Wistar …
Angiotensin II (ANGII) plays a central role in the enhanced sodium reabsorption in early type 1 diabetes in man and in streptozotocin …
Gender differences in serum and glucocorticoid regulated kinase-1 (SGK-1) expression during renal ischemia/reperfusion injury.
Rusai K, Prókai A, Szebeni B, Mészáros K, Fekete A, Szalay B, Vannay Á, Degrell P, Müller V, Tulassay T, Szabó AJ. Rusai K, et al. Cell Physiol Biochem. 2011;27(6):727-38. doi: 10.1159/000330081. Epub 2011 Jun 17. Cell Physiol Biochem. 2011. PMID: 21691090
The anti-apoptotic serum and glucocorticoid-regulated kinase-1 (SGK-1) is up-regulated and has a significant protective role in renal I/R. ...In vivo, in a rat model of unilateral renal I/R injury, there was a higher SGK-1 expression and phosphorylation in ma …
The anti-apoptotic serum and glucocorticoid-regulated kinase-1 (SGK-1) is up-regulated and has a significant protective role in renal …
Synchronized renal tubular cell death involves ferroptosis.
Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, Weinberg JM, Reichel CA, Bräsen JH, Kunzendorf U, Anders HJ, Stockwell BR, Green DR, Krautwald S. Linkermann A, et al. Among authors: prokai a. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16836-41. doi: 10.1073/pnas.1415518111. Epub 2014 Nov 10. Proc Natl Acad Sci U S A. 2014. PMID: 25385600 Free PMC article.
Immunosuppression with 4SC-101, a novel inhibitor of dihydroorotate dehydrogenase, in a rat model of renal transplantation.
Rusai K, Schmaderer C, Baumann M, Chmielewski S, Prókai A, Kis E, Szabó AJ, Leban J, Doblhofer R, Ammendola A, Lutz J, Heemann U. Rusai K, et al. Transplantation. 2012 Jun 15;93(11):1101-7. doi: 10.1097/TP.0b013e31824fd861. Transplantation. 2012. PMID: 22609757
BACKGROUND: 4SC-101 is a novel dihydroorotate dehydrogenase inhibitor and a blocker of interleukin (IL)-17 secretion with beneficial effects in experimental lupus and inflammatory bowel disease. ...Therefore, 4SC-101 might be a promising pharmaceutical agent …
BACKGROUND: 4SC-101 is a novel dihydroorotate dehydrogenase inhibitor and a blocker of interleukin (IL)-17 secretion with bene …
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