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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1983 1
1984 2
1988 1
1989 1
1990 2
1991 2
1992 3
1993 6
1994 5
1995 1
1996 5
1997 3
1998 5
1999 13
2000 7
2001 8
2002 16
2003 13
2004 19
2005 19
2006 16
2007 17
2008 14
2009 13
2010 25
2011 19
2012 18
2013 26
2014 24
2015 15
2016 18
2017 17
2018 16
2019 17
2020 21
2021 20
2022 16
2023 12
2024 4

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415 results

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Page 1
Congenital Long QT Syndrome.
Krahn AD, Laksman Z, Sy RW, Postema PG, Ackerman MJ, Wilde AAM, Han HC. Krahn AD, et al. JACC Clin Electrophysiol. 2022 May;8(5):687-706. doi: 10.1016/j.jacep.2022.02.017. JACC Clin Electrophysiol. 2022. PMID: 35589186 Free article. Review.
Risk stratification of patients with LQTS aims to identify those who are at increased risk of cardiac arrest or sudden cardiac death. Factors including age, sex, QTc interval, and genetic background all contribute to current risk stratification paradigms. The manage …
Risk stratification of patients with LQTS aims to identify those who are at increased risk of cardiac arrest or sudden cardiac death. Factor …
Scientific white paper on concentration-QTc modeling.
Garnett C, Bonate PL, Dang Q, Ferber G, Huang D, Liu J, Mehrotra D, Riley S, Sager P, Tornoe C, Wang Y. Garnett C, et al. J Pharmacokinet Pharmacodyn. 2018 Jun;45(3):383-397. doi: 10.1007/s10928-017-9558-5. Epub 2017 Dec 5. J Pharmacokinet Pharmacodyn. 2018. PMID: 29209907 Review.
The International Council for Harmonisation revised the E14 guideline through the questions and answers process to allow concentration-QTc (C-QTc) modeling to be used as the primary analysis for assessing the QTc interval prolongation risk of ne …
The International Council for Harmonisation revised the E14 guideline through the questions and answers process to allow concentration-QT
The Treatment of Tuberculosis.
Peloquin CA, Davies GR. Peloquin CA, et al. Clin Pharmacol Ther. 2021 Dec;110(6):1455-1466. doi: 10.1002/cpt.2261. Epub 2021 Jun 5. Clin Pharmacol Ther. 2021. PMID: 33837535 Review.
One challenge is to select drugs without overlapping adverse drug reaction profiles. QTc interval prolongation is one such concern, but to date, it has been manageable. ...
One challenge is to select drugs without overlapping adverse drug reaction profiles. QTc interval prolongation is one s …
New Perspectives on Antimicrobial Agents: Isavuconazole.
Lewis JS 2nd, Wiederhold NP, Hakki M, Thompson GR 3rd. Lewis JS 2nd, et al. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0017722. doi: 10.1128/aac.00177-22. Epub 2022 Aug 15. Antimicrob Agents Chemother. 2022. PMID: 35969068 Free PMC article. Review.
Significant advantages of isavuconazole, primarily over voriconazole but in some circumstances posaconazole as well, make it an appealing option for the management of complex patients with invasive fungal infections. These potential advantages include lack of QTc interv
Significant advantages of isavuconazole, primarily over voriconazole but in some circumstances posaconazole as well, make it an appealing op …
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis.
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, Samara M, Barbui C, Engel RR, Geddes JR, Kissling W, Stapf MP, Lässig B, Salanti G, Davis JM. Leucht S, et al. Lancet. 2013 Sep 14;382(9896):951-62. doi: 10.1016/S0140-6736(13)60733-3. Epub 2013 Jun 27. Lancet. 2013. PMID: 23810019 Review.
We also examined all-cause discontinuation, weight gain, extrapyramidal side-effects, prolactin increase, QTc prolongation, and sedation. FINDINGS: We identified 212 suitable trials, with data for 43 049 participants. ...Standardised mean differences compared with p …
We also examined all-cause discontinuation, weight gain, extrapyramidal side-effects, prolactin increase, QTc prolongation, an …
QTc prolongation, torsades de pointes, and psychotropic medications.
Beach SR, Celano CM, Noseworthy PA, Januzzi JL, Huffman JC. Beach SR, et al. Psychosomatics. 2013 Jan-Feb;54(1):1-13. doi: 10.1016/j.psym.2012.11.001. Psychosomatics. 2013. PMID: 23295003 Review.
Such patients may have baseline clinical risk factors for QTc prolongation, and many psychotropic medications may further prolong this interval. ...METHODS: We summarize current literature regarding appropriate methods of calculating the QTc
Such patients may have baseline clinical risk factors for QTc prolongation, and many psychotropic medications may further p
Treatment of Helicobacter pylori in Special Patient Populations.
Nguyen CT, Davis KA, Nisly SA, Li J. Nguyen CT, et al. Pharmacotherapy. 2019 Oct;39(10):1012-1022. doi: 10.1002/phar.2318. Epub 2019 Sep 2. Pharmacotherapy. 2019. PMID: 31400244 Review.
This review discusses H. pylori microbiology, including antibiotic resistance, and summarizes the existing evidence for first- and second-line treatment regimens that may be considered for special populations such as patients with penicillin allergies, patients with or at risk fo …
This review discusses H. pylori microbiology, including antibiotic resistance, and summarizes the existing evidence for first- and second-li …
Drug-induced QT Interval Prolongation in the Intensive Care Unit.
Etchegoyen CV, Keller GA, Mrad S, Cheng S, Di Girolamo G. Etchegoyen CV, et al. Curr Clin Pharmacol. 2017;12(4):210-222. doi: 10.2174/1574884713666180223123947. Curr Clin Pharmacol. 2017. PMID: 29473523 Review.
CONCLUSION: ICU patients are particularly prone to experience a QTc interval prolongation mainly for two reasons. In the first place, they are exposed to certain drugs that can prolong the repolarization phase, either by their mechanism of action or th …
CONCLUSION: ICU patients are particularly prone to experience a QTc interval prolongation mainly for two reasons. In th …
Azithromycin for the treatment of gastroparesis.
Potter TG, Snider KR. Potter TG, et al. Ann Pharmacother. 2013 Mar;47(3):411-5. doi: 10.1345/aph.1R541. Epub 2013 Feb 27. Ann Pharmacother. 2013. PMID: 23447477 Review.
Limitations to erythromycin include adverse reactions (nausea, vomiting, and abdominal pain), QTc interval prolongation, CYP3A-associated drug interactions, and tachyphylaxis. Azithromycin, another macrolide, has been shown to increase gastrointestinal motili …
Limitations to erythromycin include adverse reactions (nausea, vomiting, and abdominal pain), QTc interval prolongation
Risk factors for QTc-prolongation: systematic review of the evidence.
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V. Vandael E, et al. Int J Clin Pharm. 2017 Feb;39(1):16-25. doi: 10.1007/s11096-016-0414-2. Epub 2016 Dec 23. Int J Clin Pharm. 2017. PMID: 28012118 Review.
Background QTc-interval prolongation has been associated with serious adverse events, such as Torsade de Pointes and sudden cardiac death. ...Aim of the review The aim of this review is to summarize and assess the evidence for different risk factors for QT
Background QTc-interval prolongation has been associated with serious adverse events, such as Torsade de Pointes and su …
415 results