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Senolytic treatment fails to improve ovarian reserve or fertility in female mice.
Garcia DN, Hense JD, Zanini BM, Isola JVV, Prosczek JB, Ashiqueali S, Oliveira TL, Mason JB, Schadock IC, Barros CC, Stout MB, Masternak MM, Schneider A. Garcia DN, et al. Among authors: prosczek jb. Geroscience. 2024 Jun;46(3):3445-3455. doi: 10.1007/s11357-024-01089-0. Epub 2024 Feb 15. Geroscience. 2024. PMID: 38358579 Free PMC article.
Dasatinib and quercetin increase testosterone and sperm concentration in mice.
Garcia DN, Hense JD, Zanini BM, Isola JVV, Pradiee J, Prosczek JB, Alvarado-Rincón JA, Mondadori RG, Mason JB, Brieño-Enríquez MA, Barros CC, Stout MB, Masternak MM, Schneider A. Garcia DN, et al. Among authors: prosczek jb. Physiol Int. 2023 May 26;110(2):121-134. doi: 10.1556/2060.2023.00192. Print 2023 Jun 12. Physiol Int. 2023. PMID: 37235453
Senolytic treatment reverses obesity-mediated senescent cell accumulation in the ovary.
Hense JD, Garcia DN, Isola JV, Alvarado-Rincón JA, Zanini BM, Prosczek JB, Stout MB, Mason JB, Walsh PT, Brieño-Enríquez MA, Schadock I, Barros CC, Masternak MM, Schneider A. Hense JD, et al. Among authors: prosczek jb. Geroscience. 2022 Jun;44(3):1747-1759. doi: 10.1007/s11357-022-00573-9. Epub 2022 Apr 23. Geroscience. 2022. PMID: 35460445 Free PMC article.