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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1846 1
1897 1
1898 1
1899 1
1903 1
1906 2
1907 6
1908 6
1909 7
1910 8
1911 19
1912 15
1913 24
1914 18
1915 17
1916 14
1917 24
1918 16
1919 24
1920 28
1921 25
1922 42
1923 36
1924 40
1925 45
1926 43
1927 50
1928 47
1929 37
1930 56
1931 56
1932 70
1933 58
1934 50
1935 64
1936 54
1937 60
1938 63
1939 62
1940 59
1941 63
1942 61
1943 56
1944 59
1945 466
1946 1397
1947 1697
1948 1960
1949 1740
1950 3120
1951 4077
1952 4513
1953 4850
1954 5429
1955 5785
1956 5483
1957 5780
1958 5990
1959 6012
1960 6271
1961 7173
1962 8194
1963 12731
1964 17369
1965 14733
1966 15425
1967 19497
1968 23789
1969 27405
1970 28594
1971 33382
1972 37014
1973 39559
1974 43264
1975 44408
1976 44424
1977 45841
1978 47330
1979 51473
1980 54652
1981 56727
1982 61150
1983 65740
1984 70830
1985 76011
1986 79990
1987 83644
1988 89977
1989 97497
1990 105084
1991 109552
1992 114956
1993 120046
1994 126824
1995 132291
1996 135052
1997 139469
1998 146695
1999 152035
2000 162011
2001 168412
2002 174652
2003 185041
2004 198992
2005 214245
2006 229034
2007 238902
2008 248615
2009 256522
2010 272481
2011 288068
2012 301057
2013 310719
2014 315514
2015 317910
2016 312857
2017 311635
2018 315202
2019 323705
2020 347379
2021 352817
2022 337075
2023 310391
2024 328596
2025 339714
2026 62895

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9,075,964 results

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Page 1
Dysregulation of Protein S in COVID-19.
Sim MMS, Wood JP. Sim MMS, et al. Best Pract Res Clin Haematol. 2022 Sep;35(3):101376. doi: 10.1016/j.beha.2022.101376. Epub 2022 Aug 23. Best Pract Res Clin Haematol. 2022. PMID: 36494145 Free PMC article. Review.
One such mechanism is acquired deficiency of protein S (PS), a plasma protein that regulates coagulation and inflammatory processes, including complement activation and efferocytosis. ...This deficiency may be caused by consumption, degradation, or clearance …
One such mechanism is acquired deficiency of protein S (PS), a plasma protein that regulates coagulation and inflammato …
Protein S: a Central Regulator of Blood Coagulation.
Alshaikh NA. Alshaikh NA. Clin Lab. 2022 Aug 1;68(8). doi: 10.7754/Clin.Lab.2021.211010. Clin Lab. 2022. PMID: 35975485 Review.
BACKGROUND: Protein S is a central regulator of coagulation as it critically participates in down-regulation of both extrinsic and intrinsic pathways of the coagulation cascade. ...The strong association between protein S deficiency either hereditary o …
BACKGROUND: Protein S is a central regulator of coagulation as it critically participates in down-regulation of both extrinsic …
Anticoagulant protein S-New insights on interactions and functions.
Gierula M, Ahnström J. Gierula M, et al. J Thromb Haemost. 2020 Nov;18(11):2801-2811. doi: 10.1111/jth.15025. Epub 2020 Aug 24. J Thromb Haemost. 2020. PMID: 32702208 Free article. Review.
The importance of protein S in hemostatic regulation is apparent from the strong association between protein S deficiencies and increased risk for venous thrombosis. ...In this review, we provide an update on protein S and how it function …
The importance of protein S in hemostatic regulation is apparent from the strong association between protein S d …
Proteome-Scale Analysis of Protein S-Acylation Comes of Age.
Wang Y, Yang W. Wang Y, et al. J Proteome Res. 2021 Jan 1;20(1):14-26. doi: 10.1021/acs.jproteome.0c00409. Epub 2020 Nov 30. J Proteome Res. 2021. PMID: 33253586 Free PMC article. Review.
The deregulation of protein S-acylation contributes to many diseases such as cancer and neurodegenerative disorders. ...In this review, we summarized the techniques for the enrichment of S-acylated proteins or peptides, critically reviewed proteomic studies o …
The deregulation of protein S-acylation contributes to many diseases such as cancer and neurodegenerative disorders. ...In thi …
Protein S in preventing thrombosis.
Fricke DR, Chatterjee S, Majumder R. Fricke DR, et al. Aging (Albany NY). 2019 Jan 25;11(3):847-848. doi: 10.18632/aging.101798. Aging (Albany NY). 2019. PMID: 30683834 Free PMC article. No abstract available.
Protein S as cofactor for TFPI.
Hackeng TM, Rosing J. Hackeng TM, et al. Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2015-20. doi: 10.1161/ATVBAHA.108.177436. Epub 2009 Aug 6. Arterioscler Thromb Vasc Biol. 2009. PMID: 19661488 Review.
The search for the mechanism(s) underlying the APC-independent anticoagulant activity of protein S was hampered by the fact that protein S exhibited 2 seemingly identical anticoagulant activities in model systems and in plasma. ...The current review de …
The search for the mechanism(s) underlying the APC-independent anticoagulant activity of protein S was hampered by the fact th …
Protein S: a conduit between anticoagulation and inflammation.
Rigby AC, Grant MA. Rigby AC, et al. Crit Care Med. 2004 May;32(5 Suppl):S336-41. doi: 10.1097/01.ccm.0000126360.00450.f8. Crit Care Med. 2004. PMID: 15118541 Review.
Several recent investigations have attributed novel activated protein C-independent functions of protein S to the association of protein S with C4b-binding protein, thus establishing the importance of this fraction of plasma protein …
Several recent investigations have attributed novel activated protein C-independent functions of protein S to the assoc …
Protein S deficiency: a clinical perspective.
ten Kate MK, van der Meer J. ten Kate MK, et al. Haemophilia. 2008 Nov;14(6):1222-8. doi: 10.1111/j.1365-2516.2008.01775.x. Epub 2008 May 7. Haemophilia. 2008. PMID: 18479427 Review.
Protein S (PS) is an extensively studied protein with an important function in the down-regulation of thrombin generation. ...
Protein S (PS) is an extensively studied protein with an important function in the down-regulation of thrombin generati …
Vitamin K-Dependent Protein S: Beyond the Protein C Pathway.
Dahlbäck B. Dahlbäck B. Semin Thromb Hemost. 2018 Mar;44(2):176-184. doi: 10.1055/s-0037-1604092. Epub 2017 Sep 13. Semin Thromb Hemost. 2018. PMID: 28905350 Review.
Protein S in plasma has multiple anticoagulant properties and heterozygous protein S deficiency is associated with increased risk of venous thrombosis. ...The TAM receptor interaction is important for the ability of protein S to stimulate …
Protein S in plasma has multiple anticoagulant properties and heterozygous protein S deficiency is associated wi …
Activated protein C anticoagulant system dysfunction and thrombophilia in Asia.
Hamasaki N, Kuma H, Tsuda H. Hamasaki N, et al. Ann Lab Med. 2013 Jan;33(1):8-13. doi: 10.3343/alm.2013.33.1.8. Epub 2012 Dec 17. Ann Lab Med. 2013. PMID: 23301217 Free PMC article. Review.
Approximately 50% of Japanese and Chinese individuals who develop venous thrombosis have reduced activities of protein S. The abnormal sites causing the protein S molecule abnormalities are distributed throughout the protein S gene, PROS1 …
Approximately 50% of Japanese and Chinese individuals who develop venous thrombosis have reduced activities of protein S. The …
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