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Page 1
Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case.
Chiecchio L, Dagrada GP, Protheroe RK, Stockley DM, Smith AG, Orchard KH, Cross NC, Harrison CJ, Ross FM; UK Myeloma Forum. Chiecchio L, et al. Among authors: protheroe rk. Haematologica. 2009 Jul;94(7):1024-8. doi: 10.3324/haematol.2008.004440. Epub 2009 May 19. Haematologica. 2009. PMID: 19454499 Free PMC article.
The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance.
Ross FM, Chiecchio L, Dagrada G, Protheroe RK, Stockley DM, Harrison CJ, Cross NC, Szubert AJ, Drayson MT, Morgan GJ; UK Myeloma Forum. Ross FM, et al. Among authors: protheroe rk. Haematologica. 2010 Jul;95(7):1221-5. doi: 10.3324/haematol.2009.016329. Epub 2010 Apr 21. Haematologica. 2010. PMID: 20410185 Free PMC article.
Report from the European Myeloma Network on interphase FISH in multiple myeloma and related disorders.
Ross FM, Avet-Loiseau H, Ameye G, Gutiérrez NC, Liebisch P, O'Connor S, Dalva K, Fabris S, Testi AM, Jarosova M, Hodkinson C, Collin A, Kerndrup G, Kuglik P, Ladon D, Bernasconi P, Maes B, Zemanova Z, Michalova K, Michau L, Neben K, Hermansen NE, Rack K, Rocci A, Protheroe R, Chiecchio L, Poirel HA, Sonneveld P, Nyegaard M, Johnsen HE; European Myeloma Network. Ross FM, et al. Haematologica. 2012 Aug;97(8):1272-7. doi: 10.3324/haematol.2011.056176. Epub 2012 Feb 27. Haematologica. 2012. PMID: 22371180 Free PMC article.
Frequent upregulation of MYC in plasma cell leukemia.
Chiecchio L, Dagrada GP, White HE, Towsend MR, Protheroe RK, Cheung KL, Stockley DM, Orchard KH, Cross NC, Harrison CJ, Ross FM; UK Myeloma Forum. Chiecchio L, et al. Among authors: protheroe rk. Genes Chromosomes Cancer. 2009 Jul;48(7):624-36. doi: 10.1002/gcc.20670. Genes Chromosomes Cancer. 2009. PMID: 19396865
Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma.
Jenner MW, Leone PE, Walker BA, Ross FM, Johnson DC, Gonzalez D, Chiecchio L, Dachs Cabanas E, Dagrada GP, Nightingale M, Protheroe RK, Stockley D, Else M, Dickens NJ, Cross NC, Davies FE, Morgan GJ. Jenner MW, et al. Among authors: protheroe rk. Blood. 2007 Nov 1;110(9):3291-300. doi: 10.1182/blood-2007-02-075069. Epub 2007 Jul 3. Blood. 2007. PMID: 17609426 Free article.
A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value.
Walker BA, Leone PE, Chiecchio L, Dickens NJ, Jenner MW, Boyd KD, Johnson DC, Gonzalez D, Dagrada GP, Protheroe RK, Konn ZJ, Stockley DM, Gregory WM, Davies FE, Ross FM, Morgan GJ. Walker BA, et al. Among authors: protheroe rk. Blood. 2010 Oct 14;116(15):e56-65. doi: 10.1182/blood-2010-04-279596. Epub 2010 Jul 8. Blood. 2010. PMID: 20616218 Free article. Clinical Trial.
Deletions of CDKN2C in multiple myeloma: biological and clinical implications.
Leone PE, Walker BA, Jenner MW, Chiecchio L, Dagrada G, Protheroe RK, Johnson DC, Dickens NJ, Brito JL, Else M, Gonzalez D, Ross FM, Chen-Kiang S, Davies FE, Morgan GJ. Leone PE, et al. Among authors: protheroe rk. Clin Cancer Res. 2008 Oct 1;14(19):6033-41. doi: 10.1158/1078-0432.CCR-08-0347. Clin Cancer Res. 2008. PMID: 18829482 Free PMC article.