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Living in the liver: hepatic infections.
Protzer U, Maini MK, Knolle PA. Protzer U, et al. Nat Rev Immunol. 2012 Feb 24;12(3):201-13. doi: 10.1038/nri3169. Nat Rev Immunol. 2012. PMID: 22362353 Review.
Regulation of endotoxin-induced IL-6 production in liver sinusoidal endothelial cells and Kupffer cells by IL-10.
Knolle PA, Löser E, Protzer U, Duchmann R, Schmitt E, zum Büschenfelde KH, Rose-John S, Gerken G. Knolle PA, et al. Among authors: protzer u. Clin Exp Immunol. 1997 Mar;107(3):555-61. doi: 10.1046/j.1365-2249.1997.d01-959.x. Clin Exp Immunol. 1997. PMID: 9067532 Free PMC article.
Immune escape by hepatitis B viruses.
Protzer U, Schaller H. Protzer U, et al. Virus Genes. 2000;21(1-2):27-37. Virus Genes. 2000. PMID: 11022787 Review.
Presence of replicating virus in recombinant hepadnavirus stocks results from recombination and can be eliminated by the use of a packaging cell line.
Klöcker U, Oberwinkler H, Kürschner T, Protzer U. Klöcker U, et al. Among authors: protzer u. J Virol. 2003 Mar;77(5):2873-81. doi: 10.1128/jvi.77.5.2873-2881.2003. J Virol. 2003. PMID: 12584311 Free PMC article.
Hepatitis B virus-based vectors allow the elimination of viral gene expression and the insertion of foreign promoters.
Untergasser A, Protzer U. Untergasser A, et al. Among authors: protzer u. Hum Gene Ther. 2004 Feb;15(2):203-10. doi: 10.1089/104303404772680001. Hum Gene Ther. 2004. PMID: 14975192
Liver-specific expression of interferon gamma following adenoviral gene transfer controls hepatitis B virus replication in mice.
Dumortier J, Schönig K, Oberwinkler H, Löw R, Giese T, Bujard H, Schirmacher P, Protzer U. Dumortier J, et al. Among authors: protzer u. Gene Ther. 2005 Apr;12(8):668-77. doi: 10.1038/sj.gt.3302449. Gene Ther. 2005. PMID: 15647761
Sequential control of hepatitis B virus in a mouse model of acute, self-resolving hepatitis B.
von Freyend MJ, Untergasser A, Arzberger S, Oberwinkler H, Drebber U, Schirmacher P, Protzer U. von Freyend MJ, et al. Among authors: protzer u. J Viral Hepat. 2011 Mar;18(3):216-26. doi: 10.1111/j.1365-2893.2010.01302.x. J Viral Hepat. 2011. PMID: 20367794
Bioluminescence imaging allows measuring CD8 T cell function in the liver.
Stabenow D, Frings M, Trück C, Gärtner K, Förster I, Kurts C, Tüting T, Odenthal M, Dienes HP, Cederbrant K, Protzer U, Knolle PA. Stabenow D, et al. Among authors: protzer u. Hepatology. 2010 Apr;51(4):1430-7. doi: 10.1002/hep.23575. Hepatology. 2010. PMID: 20373369
Apoptosis of hepatitis B virus-infected hepatocytes prevents release of infectious virus.
Arzberger S, Hösel M, Protzer U. Arzberger S, et al. Among authors: protzer u. J Virol. 2010 Nov;84(22):11994-2001. doi: 10.1128/JVI.00653-10. Epub 2010 Aug 18. J Virol. 2010. PMID: 20719950 Free PMC article.
Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.
Lucifora J, Arzberger S, Durantel D, Belloni L, Strubin M, Levrero M, Zoulim F, Hantz O, Protzer U. Lucifora J, et al. Among authors: protzer u. J Hepatol. 2011 Nov;55(5):996-1003. doi: 10.1016/j.jhep.2011.02.015. Epub 2011 Mar 2. J Hepatol. 2011. PMID: 21376091
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