Prugh JD - Search Results

1

Thieno[2,3-b]furan-2-sulfonamides as topical carbonic anhydrase inhibitors.

Hartman GD, Halczenko W, Prugh JD, Smith RL, Sugrue MF, Mallorga P, Michelson SR, Randall WC, Schwam H, Sondey JM. Hartman GD, et al. Among authors: prugh jd. J Med Chem. 1992 Aug 7;35(16):3027-33. doi: 10.1021/jm00094a016. J Med Chem. 1992. PMID: 1501230

2

New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides.

Prugh JD, Hartman GD, Mallorga PJ, McKeever BM, Michelson SR, Murcko MA, Schwam H, Smith RL, Sondey JM, Springer JP, et al. Prugh JD, et al. J Med Chem. 1991 Jun;34(6):1805-18. doi: 10.1021/jm00110a008. J Med Chem. 1991. PMID: 2061922

3

Non-peptide GPIIb/IIIa inhibitors. 20. Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation.

Egbertson MS, Cook JJ, Bednar B, Prugh JD, Bednar RA, Gaul SL, Gould RJ, Hartman GD, Homnick CF, Holahan MA, Libby LA, Lynch JJ Jr, Lynch RJ, Sitko GR, Stranieri MT, Vassallo LM. Egbertson MS, et al. Among authors: prugh jd. J Med Chem. 1999 Jul 1;42(13):2409-21. doi: 10.1021/jm980722p. J Med Chem. 1999. PMID: 10395482

4

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 6. Trans-6-[2-(substituted-1-naphthyl)ethyl(or ethenyl)]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones.

Prugh JD, Alberts AW, Deana AA, Gilfillian JL, Huff JW, Smith RL, Wiggins JM. Prugh JD, et al. J Med Chem. 1990 Feb;33(2):758-65. doi: 10.1021/jm00164a047. J Med Chem. 1990. PMID: 2299642

5

Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors.

Egbertson MS, Bednar B, Askew BC, Bednar RA, Brashear K, Breslin MJ, Duggan ME, Fisher TE, Halczenko W, Hutchinson JH, Ihle N, Prugh JD, Wai JS, Gould RJ, Hartman GD. Egbertson MS, et al. Among authors: prugh jd. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1943-8. doi: 10.1016/s0960-894x(00)00385-1. Bioorg Med Chem Lett. 2000. PMID: 10987423

6

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 1. Structural modification of 5-substituted 3,5-dihydroxypentanoic acids and their lactone derivatives.

Stokker GE, Hoffman WF, Alberts AW, Cragoe EJ Jr, Deana AA, Gilfillan JL, Huff JW, Novello FC, Prugh JD, Smith RL, et al. Stokker GE, et al. Among authors: prugh jd. J Med Chem. 1985 Mar;28(3):347-58. doi: 10.1021/jm00381a014. J Med Chem. 1985. PMID: 3973903

7

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 2. Structural modification of 7-(substituted aryl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives.

Hoffman WF, Alberts AW, Cragoe EJ Jr, Deana AA, Evans BE, Gilfillan JL, Gould NP, Huff JW, Novello FC, Prugh JD, et al. Hoffman WF, et al. Among authors: prugh jd. J Med Chem. 1986 Feb;29(2):159-69. doi: 10.1021/jm00152a001. J Med Chem. 1986. PMID: 3950901

8

Inhibitors of gastric acid secretion: antisecretory 2-pyridylurea derivatives.

Bolhofer WA, Deana AA, Habecker CN, Hoffman JM, Gould NP, Pietruszkiewicz AM, Prugh JD, Torchiana ML, Cragoe EJ Jr, Hirschmann R. Bolhofer WA, et al. Among authors: prugh jd. J Med Chem. 1983 Apr;26(4):538-44. doi: 10.1021/jm00358a015. J Med Chem. 1983. PMID: 6834386

9

Heterocyclic amines. 3. 3-Dimethylaminofuran.

Prugh JD, McCarthy WC. Prugh JD, et al. J Med Chem. 1966 Mar;9(2):254-5. doi: 10.1021/jm00320a029. J Med Chem. 1966. PMID: 5911810 No abstract available.

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