Ptak RG - Search Results

1

An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.

Bennett RP, Stewart RA, Hogan PA, Ptak RG, Mankowski MK, Hartman TL, Buckheit RW Jr, Snyder BA, Salter JD, Morales GA, Smith HC. Bennett RP, et al. Among authors: ptak rg. Antiviral Res. 2016 Dec;136:51-59. doi: 10.1016/j.antiviral.2016.11.001. Epub 2016 Nov 5. Antiviral Res. 2016. PMID: 27825797 Free PMC article.

2

Antiviral activity of hop constituents against a series of DNA and RNA viruses.

Buckwold VE, Wilson RJ, Nalca A, Beer BB, Voss TG, Turpin JA, Buckheit RW 3rd, Wei J, Wenzel-Mathers M, Walton EM, Smith RJ, Pallansch M, Ward P, Wells J, Chuvala L, Sloane S, Paulman R, Russell J, Hartman T, Ptak R. Buckwold VE, et al. Antiviral Res. 2004 Jan;61(1):57-62. doi: 10.1016/s0166-3542(03)00155-4. Antiviral Res. 2004. PMID: 14670594

3

Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef.

Ptak RG, Gentry BG, Hartman TL, Watson KM, Osterling MC, Buckheit RW Jr, Townsend LB, Drach JC. Ptak RG, et al. Antimicrob Agents Chemother. 2010 Apr;54(4):1512-9. doi: 10.1128/AAC.01443-09. Epub 2010 Jan 19. Antimicrob Agents Chemother. 2010. PMID: 20086149 Free PMC article.

4

A novel anti-HIV active integrase inhibitor with a favorable in vitro cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase metabolism profile.

Okello MO, Mishra S, Nishonov M, Mankowski MK, Russell JD, Wei J, Hogan PA, Ptak RG, Nair V. Okello MO, et al. Among authors: ptak rg. Antiviral Res. 2013 Jun;98(3):365-72. doi: 10.1016/j.antiviral.2013.04.005. Epub 2013 Apr 18. Antiviral Res. 2013. PMID: 23602851 Free PMC article.

5

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein.

Pery E, Sheehy A, Nebane NM, Brazier AJ, Misra V, Rajendran KS, Buhrlage SJ, Mankowski MK, Rasmussen L, White EL, Ptak RG, Gabuzda D. Pery E, et al. Among authors: ptak rg. J Biol Chem. 2015 Apr 17;290(16):10504-17. doi: 10.1074/jbc.M114.626903. Epub 2015 Feb 27. J Biol Chem. 2015. PMID: 25724652 Free PMC article.

6

Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1.

Pery E, Sheehy A, Miranda Nebane N, Misra V, Mankowski MK, Rasmussen L, Lucile White E, Ptak RG, Gabuzda D. Pery E, et al. Among authors: ptak rg. Virology. 2015 Oct;484:276-287. doi: 10.1016/j.virol.2015.06.014. Epub 2015 Jul 1. Virology. 2015. PMID: 26141568 Free PMC article.

7

In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor.

Javanbakht H, Ptak RG, Chow E, Yan JM, Russell JD, Mankowski MK, Hogan PA, Hogg JH, Vora H, Hang JQ, Li Y, Su G, Paul A, Cammack N, Klumpp K, Heilek G. Javanbakht H, et al. Among authors: ptak rg. Antiviral Res. 2010 May;86(2):212-9. doi: 10.1016/j.antiviral.2010.02.323. Epub 2010 Feb 26. Antiviral Res. 2010. PMID: 20219553

8

Potent strategy to inhibit HIV-1 by binding both gp120 and gp41.

Kagiampakis I, Gharibi A, Mankowski MK, Snyder BA, Ptak RG, Alatas K, LiWang PJ. Kagiampakis I, et al. Among authors: ptak rg. Antimicrob Agents Chemother. 2011 Jan;55(1):264-75. doi: 10.1128/AAC.00376-10. Epub 2010 Oct 18. Antimicrob Agents Chemother. 2011. PMID: 20956603 Free PMC article.

9

Structure-activity relationship studies of indole-based compounds as small molecule HIV-1 fusion inhibitors targeting glycoprotein 41.

Zhou G, Sofiyev V, Kaur H, Snyder BA, Mankowski MK, Hogan PA, Ptak RG, Gochin M. Zhou G, et al. Among authors: ptak rg. J Med Chem. 2014 Jun 26;57(12):5270-81. doi: 10.1021/jm500344y. Epub 2014 Jun 6. J Med Chem. 2014. PMID: 24856833 Free PMC article.

10

Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication.

Wang D, Iera J, Baker H, Hogan P, Ptak R, Yang L, Hartman T, Buckheit RW Jr, Desjardins A, Yang A, Legault P, Yedavalli V, Jeang KT, Appella DH. Wang D, et al. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6893-7. doi: 10.1016/j.bmcl.2009.10.078. Epub 2009 Oct 23. Bioorg Med Chem Lett. 2009. PMID: 19896372 Free PMC article.

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