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Signaling via the IL-2 and IL-7 receptors from the membrane to the nucleus.
Leonard WJ, Imada K, Nakajima H, Puel A, Soldaini E, John S. Leonard WJ, et al. Among authors: puel a. Cold Spring Harb Symp Quant Biol. 1999;64:417-24. doi: 10.1101/sqb.1999.64.417. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232316 Review. No abstract available.
IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells.
Davidson DJ, Currie AJ, Bowdish DM, Brown KL, Rosenberger CM, Ma RC, Bylund J, Campsall PA, Puel A, Picard C, Casanova JL, Turvey SE, Hancock RE, Devon RS, Speert DP. Davidson DJ, et al. Among authors: puel a. J Immunol. 2006 Dec 1;177(11):8202-11. doi: 10.4049/jimmunol.177.11.8202. J Immunol. 2006. PMID: 17114497 Free PMC article.
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans.
Isnardi I, Ng YS, Srdanovic I, Motaghedi R, Rudchenko S, von Bernuth H, Zhang SY, Puel A, Jouanguy E, Picard C, Garty BZ, Camcioglu Y, Doffinger R, Kumararatne D, Davies G, Gallin JI, Haraguchi S, Day NK, Casanova JL, Meffre E. Isnardi I, et al. Among authors: puel a. Immunity. 2008 Nov 14;29(5):746-57. doi: 10.1016/j.immuni.2008.09.015. Immunity. 2008. PMID: 19006693 Free PMC article.
Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG/NEMO mutations.
Miot C, Imai K, Imai C, Mancini AJ, Kucuk ZY, Kawai T, Nishikomori R, Ito E, Pellier I, Dupuis Girod S, Rosain J, Sasaki S, Chandrakasan S, Pachlopnik Schmid J, Okano T, Colin E, Olaya-Vargas A, Yamazaki-Nakashimada M, Qasim W, Espinosa Padilla S, Jones A, Krol A, Cole N, Jolles S, Bleesing J, Vraetz T, Gennery AR, Abinun M, Güngör T, Costa-Carvalho B, Condino-Neto A, Veys P, Holland SM, Uzel G, Moshous D, Neven B, Blanche S, Ehl S, Döffinger R, Patel SY, Puel A, Bustamante J, Gelfand EW, Casanova JL, Orange JS, Picard C. Miot C, et al. Among authors: puel a. Blood. 2017 Sep 21;130(12):1456-1467. doi: 10.1182/blood-2017-03-771600. Epub 2017 Jul 5. Blood. 2017. PMID: 28679735 Free PMC article.
Pyogenic bacterial infections in humans with IRAK-4 deficiency.
Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, Elbim C, Hitchcock R, Lammas D, Davies G, Al-Ghonaium A, Al-Rayes H, Al-Jumaah S, Al-Hajjar S, Al-Mohsen IZ, Frayha HH, Rucker R, Hawn TR, Aderem A, Tufenkeji H, Haraguchi S, Day NK, Good RA, Gougerot-Pocidalo MA, Ozinsky A, Casanova JL. Picard C, et al. Among authors: puel a. Science. 2003 Mar 28;299(5615):2076-9. doi: 10.1126/science.1081902. Epub 2003 Mar 13. Science. 2003. PMID: 12637671
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