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Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart.
Barger JL, Kayo T, Pugh TD, Prolla TA, Weindruch R. Barger JL, et al. Among authors: pugh td. Exp Gerontol. 2008 Sep;43(9):859-66. doi: 10.1016/j.exger.2008.06.013. Epub 2008 Jul 9. Exp Gerontol. 2008. PMID: 18657603
The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gamma.
Someya S, Yamasoba T, Kujoth GC, Pugh TD, Weindruch R, Tanokura M, Prolla TA. Someya S, et al. Among authors: pugh td. Neurobiol Aging. 2008 Jul;29(7):1080-92. doi: 10.1016/j.neurobiolaging.2007.01.014. Epub 2007 Mar 23. Neurobiol Aging. 2008. PMID: 17363114 Free PMC article.
The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice.
Lee CK, Pugh TD, Klopp RG, Edwards J, Allison DB, Weindruch R, Prolla TA. Lee CK, et al. Free Radic Biol Med. 2004 Apr 15;36(8):1043-57. doi: 10.1016/j.freeradbiomed.2004.01.015. Free Radic Biol Med. 2004. PMID: 15059645
Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction.
Martin SA, DeMuth TM, Miller KN, Pugh TD, Polewski MA, Colman RJ, Eliceiri KW, Beasley TM, Johnson SC, Anderson RM. Martin SA, et al. Among authors: pugh td. Aging Cell. 2016 Feb;15(1):100-10. doi: 10.1111/acel.12418. Epub 2015 Nov 2. Aging Cell. 2016. PMID: 26521867 Free PMC article.
Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study.
Sridharan A, Pehar M, Salamat MS, Pugh TD, Bendlin BB, Willette AA, Anderson RM, Kemnitz JW, Colman RJ, Weindruch RH, Puglielli L, Johnson SC. Sridharan A, et al. Among authors: pugh td. Brain Res. 2013 May 1;1508:1-8. doi: 10.1016/j.brainres.2013.02.046. Epub 2013 Mar 7. Brain Res. 2013. PMID: 23473840 Free PMC article.
A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys.
Pugh TD, Conklin MW, Evans TD, Polewski MA, Barbian HJ, Pass R, Anderson BD, Colman RJ, Eliceiri KW, Keely PJ, Weindruch R, Beasley TM, Anderson RM. Pugh TD, et al. Aging Cell. 2013 Aug;12(4):672-81. doi: 10.1111/acel.12091. Epub 2013 May 27. Aging Cell. 2013. PMID: 23607901 Free PMC article.
A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by SIRT3.
Barger JL, Anderson RM, Newton MA, da Silva C, Vann JA, Pugh TD, Someya S, Prolla TA, Weindruch R. Barger JL, et al. Among authors: pugh td. PLoS One. 2015 Apr 1;10(4):e0120738. doi: 10.1371/journal.pone.0120738. eCollection 2015. PLoS One. 2015. PMID: 25830335 Free PMC article.
Gene expression profiling reveals differential effects of sodium selenite, selenomethionine, and yeast-derived selenium in the mouse.
Barger JL, Kayo T, Pugh TD, Vann JA, Power R, Dawson K, Weindruch R, Prolla TA. Barger JL, et al. Among authors: pugh td. Genes Nutr. 2012 Apr;7(2):155-65. doi: 10.1007/s12263-011-0243-9. Epub 2011 Aug 17. Genes Nutr. 2012. PMID: 21847681 Free PMC article.
Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics.
Barger JL, Vann JM, Cray NL, Pugh TD, Mastaloudis A, Hester SN, Wood SM, Newton MA, Weindruch R, Prolla TA. Barger JL, et al. Among authors: pugh td. Aging Cell. 2017 Aug;16(4):750-760. doi: 10.1111/acel.12608. Epub 2017 May 26. Aging Cell. 2017. PMID: 28556428 Free PMC article.
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