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Normal responses to injury prevent systemic inflammation and can be immunosuppressive.
Munford RS, Pugin J. Munford RS, et al. Am J Respir Crit Care Med. 2001 Feb;163(2):316-21. doi: 10.1164/ajrccm.163.2.2007102. Am J Respir Crit Care Med. 2001. PMID: 11179099 Review. No abstract available.
Cytokine balance in the lungs of patients with acute respiratory distress syndrome.
Park WY, Goodman RB, Steinberg KP, Ruzinski JT, Radella F 2nd, Park DR, Pugin J, Skerrett SJ, Hudson LD, Martin TR. Park WY, et al. Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 1):1896-903. doi: 10.1164/ajrccm.164.10.2104013. Am J Respir Crit Care Med. 2001. PMID: 11734443
Local inflammatory responses following bronchial endotoxin instillation in humans.
O'Grady NP, Preas HL, Pugin J, Fiuza C, Tropea M, Reda D, Banks SM, Suffredini AF. O'Grady NP, et al. Am J Respir Crit Care Med. 2001 Jun;163(7):1591-8. doi: 10.1164/ajrccm.163.7.2009111. Am J Respir Crit Care Med. 2001. PMID: 11401879
Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1beta-dependent mechanism.
Geiser T, Atabai K, Jarreau PH, Ware LB, Pugin J, Matthay MA. Geiser T, et al. Am J Respir Crit Care Med. 2001 May;163(6):1384-8. doi: 10.1164/ajrccm.163.6.2006131. Am J Respir Crit Care Med. 2001. PMID: 11371405
CC chemokines and interleukin-5 in bronchial lavage fluid from patients with status asthmaticus. Potential implication in eosinophil recruitment.
Tillie-Leblond I, Hammad H, Desurmont S, Pugin J, Wallaert B, Tonnel AB, Gosset P. Tillie-Leblond I, et al. Am J Respir Crit Care Med. 2000 Aug;162(2 Pt 1):586-92. doi: 10.1164/ajrccm.162.2.9907014. Am J Respir Crit Care Med. 2000. PMID: 10934091
Year in review in Intensive Care Medicine, 2007. II. Haemodynamics, pneumonia, infections and sepsis, invasive and non-invasive mechanical ventilation, acute respiratory distress syndrome.
Antonelli M, Azoulay E, Bonten M, Chastre J, Citerio G, Conti G, De Backer D, Lemaire F, Gerlach H, Groeneveld J, Hedenstierna G, Macrae D, Mancebo J, Maggiore SM, Mebazaa A, Metnitz P, Pugin J, Wernerman J, Zhang H. Antonelli M, et al. Intensive Care Med. 2008 Mar;34(3):405-22. doi: 10.1007/s00134-008-1009-8. Epub 2008 Jan 31. Intensive Care Med. 2008. PMID: 18236026 Review. No abstract available.
Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide.
Sellati TJ, Bouis DA, Kitchens RL, Darveau RP, Pugin J, Ulevitch RJ, Gangloff SC, Goyert SM, Norgard MV, Radolf JD. Sellati TJ, et al. J Immunol. 1998 Jun 1;160(11):5455-64. J Immunol. 1998. PMID: 9605148
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