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431 results
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TLRs as therapeutic targets in CNS inflammation and infection.
Pedras-Vasconcelos J, Puig M, Verthelyi D. Pedras-Vasconcelos J, et al. Front Biosci (Elite Ed). 2009 Jun 1;1:476-87. doi: 10.2741/e43. Front Biosci (Elite Ed). 2009. PMID: 19482661 Review.
CpG oligodeoxynucleotides protect newborn mice from a lethal challenge with the neurotropic Tacaribe arenavirus.
Pedras-Vasconcelos JA, Goucher D, Puig M, Tonelli LH, Wang V, Ito S, Verthelyi D. Pedras-Vasconcelos JA, et al. J Immunol. 2006 Apr 15;176(8):4940-9. doi: 10.4049/jimmunol.176.8.4940. J Immunol. 2006. PMID: 16585590
Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: structural studies and immunomodulatory activity in primates.
Puig M, Grajkowski A, Boczkowska M, Ausín C, Beaucage SL, Verthelyi D. Puig M, et al. Nucleic Acids Res. 2006;34(22):6488-95. doi: 10.1093/nar/gkl867. Epub 2006 Nov 27. Nucleic Acids Res. 2006. PMID: 17130156 Free PMC article.
Immunotherapy with CpG oligonucleotides and antibodies to TNF-alpha rescues neonatal mice from lethal arenavirus-induced meningoencephalitis.
Pedras-Vasconcelos JA, Puig M, Sauder C, Wolbert C, Ovanesov M, Goucher D, Verthelyi D. Pedras-Vasconcelos JA, et al. J Immunol. 2008 Jun 15;180(12):8231-40. doi: 10.4049/jimmunol.180.12.8231. J Immunol. 2008. PMID: 18523289
TLR9 and TLR7 agonists mediate distinct type I IFN responses in humans and nonhuman primates in vitro and in vivo.
Puig M, Tosh KW, Schramm LM, Grajkowska LT, Kirschman KD, Tami C, Beren J, Rabin RL, Verthelyi D. Puig M, et al. J Leukoc Biol. 2012 Jan;91(1):147-58. doi: 10.1189/jlb.0711371. Epub 2011 Nov 4. J Leukoc Biol. 2012. PMID: 22058422
High-throughput quantitative real-time polymerase chain reaction array for absolute and relative quantification of rhesus macaque types I, II, and III interferon and their subtypes.
Schramm LM, Kirschman KD, Heuer M, Chen AA, Verthelyi D, Puig M, Rabin RL. Schramm LM, et al. J Interferon Cytokine Res. 2012 Sep;32(9):407-15. doi: 10.1089/jir.2012.0015. Epub 2012 Jul 20. J Interferon Cytokine Res. 2012. PMID: 22817480 Free PMC article.
Detection of innate immune response modulating impurities in therapeutic proteins.
Haile LA, Puig M, Kelley-Baker L, Verthelyi D. Haile LA, et al. PLoS One. 2015 Apr 22;10(4):e0125078. doi: 10.1371/journal.pone.0125078. eCollection 2015. PLoS One. 2015. PMID: 25901912 Free PMC article.
Immune-mediated pathology in Duchenne muscular dystrophy.
Rosenberg AS, Puig M, Nagaraju K, Hoffman EP, Villalta SA, Rao VA, Wakefield LM, Woodcock J. Rosenberg AS, et al. Sci Transl Med. 2015 Aug 5;7(299):299rv4. doi: 10.1126/scitranslmed.aaa7322. Sci Transl Med. 2015. PMID: 26246170 Free PMC article. Review.
In Vivo Effect of Innate Immune Response Modulating Impurities on the Skin Milieu Using a Macaque Model: Impact on Product Immunogenicity.
Haile LA, Puig M, Polumuri SK, Ascher J, Verthelyi D. Haile LA, et al. J Pharm Sci. 2017 Mar;106(3):751-760. doi: 10.1016/j.xphs.2016.11.001. Epub 2016 Dec 4. J Pharm Sci. 2017. PMID: 27923493
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