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The complex pathways of Wnt 5a in cancer progression.
Pukrop T, Binder C. Pukrop T, et al. J Mol Med (Berl). 2008 Mar;86(3):259-66. doi: 10.1007/s00109-007-0266-2. Epub 2007 Oct 19. J Mol Med (Berl). 2008. PMID: 17952396 Review.
Antagonistic regulation of convergent extension movements in Xenopus by Wnt/beta-catenin and Wnt/Ca2+ signaling.
Kühl M, Geis K, Sheldahl LC, Pukrop T, Moon RT, Wedlich D. Kühl M, et al. Among authors: pukrop t. Mech Dev. 2001 Aug;106(1-2):61-76. doi: 10.1016/s0925-4773(01)00416-6. Mech Dev. 2001. PMID: 11472835
Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells.
Hagemann T, Binder C, Binder L, Pukrop T, Trümper L, Grimshaw MJ. Hagemann T, et al. Among authors: pukrop t. DNA Cell Biol. 2005 Nov;24(11):766-76. doi: 10.1089/dna.2005.24.766. DNA Cell Biol. 2005. PMID: 16274297
Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines.
Pukrop T, Klemm F, Hagemann T, Gradl D, Schulz M, Siemes S, Trümper L, Binder C. Pukrop T, et al. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5454-9. doi: 10.1073/pnas.0509703103. Epub 2006 Mar 28. Proc Natl Acad Sci U S A. 2006. PMID: 16569699 Free PMC article.
Stromal endothelin B receptor-deficiency inhibits breast cancer growth and metastasis.
Binder C, Hagemann T, Sperling S, Schulz M, Pukrop T, Grimshaw MJ, Ehrenreich H. Binder C, et al. Among authors: pukrop t. Mol Cancer Ther. 2009 Aug;8(8):2452-60. doi: 10.1158/1535-7163.MCT-09-0032. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671740 Free PMC article.
Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way.
Pukrop T, Dehghani F, Chuang HN, Lohaus R, Bayanga K, Heermann S, Regen T, Van Rossum D, Klemm F, Schulz M, Siam L, Hoffmann A, Trümper L, Stadelmann C, Bechmann I, Hanisch UK, Binder C. Pukrop T, et al. Glia. 2010 Sep;58(12):1477-89. doi: 10.1002/glia.21022. Glia. 2010. PMID: 20549749
β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis.
Klemm F, Bleckmann A, Siam L, Chuang HN, Rietkötter E, Behme D, Schulz M, Schaffrinski M, Schindler S, Trümper L, Kramer F, Beissbarth T, Stadelmann C, Binder C, Pukrop T. Klemm F, et al. Among authors: pukrop t. Carcinogenesis. 2011 Mar;32(3):434-42. doi: 10.1093/carcin/bgq269. Epub 2010 Dec 20. Carcinogenesis. 2011. PMID: 21173432
Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.
Kendziorra E, Ahlborn K, Spitzner M, Rave-Fränk M, Emons G, Gaedcke J, Kramer F, Wolff HA, Becker H, Beissbarth T, Ebner R, Ghadimi BM, Pukrop T, Ried T, Grade M. Kendziorra E, et al. Among authors: pukrop t. Carcinogenesis. 2011 Dec;32(12):1824-31. doi: 10.1093/carcin/bgr222. Epub 2011 Oct 8. Carcinogenesis. 2011. PMID: 21983179 Free PMC article.
This effect was restricted to tumor cells with high T cell factor (TCF) reporter activity, presumably in a β-catenin-independent manner. ...
This effect was restricted to tumor cells with high T cell factor (TCF) reporter activity, presumably in a β-catenin-independent mann …
Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas.
Bleckmann A, Siam L, Klemm F, Rietkötter E, Wegner C, Kramer F, Beissbarth T, Binder C, Stadelmann C, Pukrop T. Bleckmann A, et al. Among authors: pukrop t. Clin Exp Metastasis. 2013 Apr;30(4):471-82. doi: 10.1007/s10585-012-9552-7. Epub 2012 Dec 8. Clin Exp Metastasis. 2013. PMID: 23224985 Free PMC article.
Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion.
Rietkötter E, Menck K, Bleckmann A, Farhat K, Schaffrinski M, Schulz M, Hanisch UK, Binder C, Pukrop T. Rietkötter E, et al. Among authors: pukrop t. Oncotarget. 2013 Sep;4(9):1449-60. doi: 10.18632/oncotarget.1201. Oncotarget. 2013. PMID: 24036536 Free PMC article.
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