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Drug delivery system based on chronobiology--A review.
Mandal AS, Biswas N, Karim KM, Guha A, Chatterjee S, Behera M, Kuotsu K. Mandal AS, et al. J Control Release. 2010 Nov 1;147(3):314-25. doi: 10.1016/j.jconrel.2010.07.122. Epub 2010 Aug 4. J Control Release. 2010. PMID: 20691738 Review.
However the major drawback in the development of such delivery system that matches the circadian rhythm requires the availability of precise technology (pulsatile drug delivery). The increasing research interest surrounding this delive
However the major drawback in the development of such delivery system that matches the circadian rhythm requires the availabil …
Thermoresponsive gating membranes embedded with liquid crystal(s) for pulsatile transdermal drug delivery: An overview and perspectives.
Lin SY. Lin SY. J Control Release. 2020 Mar 10;319:450-474. doi: 10.1016/j.jconrel.2019.12.046. Epub 2019 Dec 31. J Control Release. 2020. PMID: 31901369 Review.
For many drugs, it is not always necessary to constantly deliver a drug into the human body under disease conditions due to rhythmic variations. Pulsatile drug delivery systems (PDDSs) have been receiving more attention in pharmaceutical develop …
For many drugs, it is not always necessary to constantly deliver a drug into the human body under disease conditions due to rhythmic …
Patented pulsatile drug delivery technologies for chronotherapy.
Patil SS, Shahiwala A. Patil SS, et al. Expert Opin Ther Pat. 2014 Aug;24(8):845-56. doi: 10.1517/13543776.2014.916281. Epub 2014 May 8. Expert Opin Ther Pat. 2014. PMID: 24810112 Review.
AREAS COVERED: The present review discusses in depth on recent patents and developments related to pulsatile drug delivery systems with eroding, soluble or rupturable barrier coatings, and systems with capsular structures. Besides focusin …
AREAS COVERED: The present review discusses in depth on recent patents and developments related to pulsatile drug de
An Implantable Drug-delivery System on a Chip.
Lee MS, Yao DJ, Hsu W. Lee MS, et al. Curr Top Med Chem. 2015;15(15):1516-24. doi: 10.2174/1568026615666150414121427. Curr Top Med Chem. 2015. PMID: 25877094 Review.
An implantable system for drug delivery provides a new strategy for drug therapy, and typically involves a microfluidic chip produced with micro or nano-technology. ...We here review the implantable drug-delivery system
An implantable system for drug delivery provides a new strategy for drug therapy, and typically involves a micro …
Drug delivery systems with modified release for systemic and biophase bioavailability.
Leucuta SE. Leucuta SE. Curr Clin Pharmacol. 2012 Nov;7(4):282-317. doi: 10.2174/157488412803305786. Curr Clin Pharmacol. 2012. PMID: 22794159 Review.
This paper describes the biopharmaceutical, pharmacokinetic, pharmacologic and technological principles in the design of drug delivery systems with modified release as well as the formulation criteria of prolonged and controlled release drug deliver
This paper describes the biopharmaceutical, pharmacokinetic, pharmacologic and technological principles in the design of drug deli
Osmotic drug delivery systems: basics and design approaches.
Patra CN, Swain S, Sruti J, Patro AP, Panigrahi KC, Beg S, Rao ME. Patra CN, et al. Recent Pat Drug Deliv Formul. 2013 Aug;7(2):150-61. doi: 10.2174/1872211311307020007. Recent Pat Drug Deliv Formul. 2013. PMID: 23286513 Review.
Osmotic drug delivery system utilizes the principles of osmotic pressure for the controlled delivery of active pharmaceutical ingredient at a predetermined zero order rate. ...The major arena of this review is to highlight about the different ty …
Osmotic drug delivery system utilizes the principles of osmotic pressure for the controlled delivery of active p …
Implantable microchip: the futuristic controlled drug delivery system.
Sutradhar KB, Sumi CD. Sutradhar KB, et al. Drug Deliv. 2016;23(1):1-11. doi: 10.3109/10717544.2014.903579. Epub 2014 Apr 24. Drug Deliv. 2016. PMID: 24758139 Free article. Review.
There is no doubt that controlled and pulsatile drug delivery system is an important challenge in medicine over the conventional drug delivery system in case of therapeutic efficacy. ...More recently, some elegant study has noted t …
There is no doubt that controlled and pulsatile drug delivery system is an important challenge in medicine over …
3D Printing in Personalized Drug Delivery.
Afsana, Jain V, Haider N, Jain K. Afsana, et al. Curr Pharm Des. 2018;24(42):5062-5071. doi: 10.2174/1381612825666190215122208. Curr Pharm Des. 2018. PMID: 30767736 Review.
METHODS: 3D printing technology uses digitally controlled devices for formulating API and excipients in a layer by layer pattern for developing a suitable personalized drug delivery system as per the need of patient. ...Further 3D printing based
METHODS: 3D printing technology uses digitally controlled devices for formulating API and excipients in a layer by layer patte
The local pulsatile parathyroid hormone delivery system induces the osteogenic differentiation of dental pulp mesenchymal stem cells to reconstruct mandibular defects.
Jia Y, Duan M, Yang Y, Li D, Wang D, Tang Z. Jia Y, et al. Stem Cell Res Ther. 2025 Mar 6;16(1):119. doi: 10.1186/s13287-025-04258-w. Stem Cell Res Ther. 2025. PMID: 40050973 Free PMC article.
METHODS: Pulsatile delivery systems, both with and without PTH, were developed following the protocols outlined in our previous study. In vitro, the biocompatibility of the pulsatile delivery system with DPSCs was assessed using th
METHODS: Pulsatile delivery systems, both with and without PTH, were developed following the protocols outlined
Site specific chronotherapeutic drug delivery systems: a patent review.
Saigal N, Baboota S, Ahuja A, Ali J. Saigal N, et al. Recent Pat Drug Deliv Formul. 2009 Jan;3(1):64-70. doi: 10.2174/187221109787158328. Recent Pat Drug Deliv Formul. 2009. PMID: 19149730 Review.
In such cases a pulsatile drug delivery may be more advantageous. Pulsatile drug delivery systems can be classified into site-specific systems in which the drug is released at the desired site within the intestinal tr …
In such cases a pulsatile drug delivery may be more advantageous. Pulsatile drug delivery syste
22 results