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The HLA A*0201-restricted hTERT(540-548) peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor.
Purbhoo MA, Li Y, Sutton DH, Brewer JE, Gostick E, Bossi G, Laugel B, Moysey R, Baston E, Liddy N, Cameron B, Bennett AD, Ashfield R, Milicic A, Price DA, Classon BJ, Sewell AK, Jakobsen BK. Purbhoo MA, et al. Mol Cancer Ther. 2007 Jul;6(7):2081-91. doi: 10.1158/1535-7163.MCT-07-0092. Mol Cancer Ther. 2007. PMID: 17620437 Free article.
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor.
Varela-Rohena A, Molloy PE, Dunn SM, Li Y, Suhoski MM, Carroll RG, Milicic A, Mahon T, Sutton DH, Laugel B, Moysey R, Cameron BJ, Vuidepot A, Purbhoo MA, Cole DK, Phillips RE, June CH, Jakobsen BK, Sewell AK, Riley JL. Varela-Rohena A, et al. Among authors: purbhoo ma. Nat Med. 2008 Dec;14(12):1390-5. doi: 10.1038/nm.1779. Epub 2008 Nov 9. Nat Med. 2008. PMID: 18997777 Free PMC article.
Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.
Sewell AK, Gerth UC, Price DA, Purbhoo MA, Boulter JM, Gao GF, Bell JI, Phillips RE, Jakobsen BK. Sewell AK, et al. Among authors: purbhoo ma. Nat Med. 1999 Apr;5(4):399-404. doi: 10.1038/7398. Nat Med. 1999. PMID: 10202928
The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.
Purbhoo MA, Boulter JM, Price DA, Vuidepot AL, Hourigan CS, Dunbar PR, Olson K, Dawson SJ, Phillips RE, Jakobsen BK, Bell JI, Sewell AK. Purbhoo MA, et al. J Biol Chem. 2001 Aug 31;276(35):32786-92. doi: 10.1074/jbc.M102498200. Epub 2001 Jul 3. J Biol Chem. 2001. PMID: 11438524 Free article.
A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex.
Xu XN, Purbhoo MA, Chen N, Mongkolsapaya J, Cox JH, Meier UC, Tafuro S, Dunbar PR, Sewell AK, Hourigan CS, Appay V, Cerundolo V, Burrows SR, McMichael AJ, Screaton GR. Xu XN, et al. Among authors: purbhoo ma. Immunity. 2001 May;14(5):591-602. doi: 10.1016/s1074-7613(01)00133-9. Immunity. 2001. PMID: 11371361 Free article.
36 results