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Exon Skipping Therapy.
Young CS, Pyle AD. Young CS, et al. Among authors: pyle ad. Cell. 2016 Nov 17;167(5):1144. doi: 10.1016/j.cell.2016.10.050. Cell. 2016. PMID: 27863231 Free article.
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.
Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE. Chin MH, et al. Among authors: pyle ad. Cell Stem Cell. 2009 Jul 2;5(1):111-23. doi: 10.1016/j.stem.2009.06.008. Cell Stem Cell. 2009. PMID: 19570518 Free PMC article.
Female human iPSCs retain an inactive X chromosome.
Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. Tchieu J, et al. Among authors: pyle ad. Cell Stem Cell. 2010 Sep 3;7(3):329-42. doi: 10.1016/j.stem.2010.06.024. Epub 2010 Aug 19. Cell Stem Cell. 2010. PMID: 20727844 Free PMC article.
A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells.
Young CS, Hicks MR, Ermolova NV, Nakano H, Jan M, Younesi S, Karumbayaram S, Kumagai-Cresse C, Wang D, Zack JA, Kohn DB, Nakano A, Nelson SF, Miceli MC, Spencer MJ, Pyle AD. Young CS, et al. Among authors: pyle ad. Cell Stem Cell. 2016 Apr 7;18(4):533-40. doi: 10.1016/j.stem.2016.01.021. Epub 2016 Feb 11. Cell Stem Cell. 2016. PMID: 26877224 Free PMC article.
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
Lee PC, Truong B, Vega-Crespo A, Gilmore WB, Hermann K, Angarita SA, Tang JK, Chang KM, Wininger AE, Lam AK, Schoenberg BE, Cederbaum SD, Pyle AD, Byrne JA, Lipshutz GS. Lee PC, et al. Among authors: pyle ad. Mol Ther Nucleic Acids. 2016 Nov 29;5(11):e394. doi: 10.1038/mtna.2016.98. Mol Ther Nucleic Acids. 2016. PMID: 27898091 Free PMC article.
In Vivo Human Somitogenesis Guides Somite Development from hPSCs.
Xi H, Fujiwara W, Gonzalez K, Jan M, Liebscher S, Van Handel B, Schenke-Layland K, Pyle AD. Xi H, et al. Among authors: pyle ad. Cell Rep. 2017 Feb 7;18(6):1573-1585. doi: 10.1016/j.celrep.2017.01.040. Cell Rep. 2017. PMID: 28178531 Free PMC article.
57 results