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Visualizing group II intron catalysis through the stages of splicing.
Marcia M, Pyle AM. Marcia M, et al. Cell. 2012 Oct 26;151(3):497-507. doi: 10.1016/j.cell.2012.09.033. Cell. 2012. PMID: 23101623 Free PMC article.
Conversion of a group II intron into a new multiple-turnover ribozyme that selectively cleaves oligonucleotides: elucidation of reaction mechanism and structure/function relationships.
Michels WJ Jr, Pyle AM. Michels WJ Jr, et al. Biochemistry. 1995 Mar 7;34(9):2965-77. doi: 10.1021/bi00009a028. Biochemistry. 1995. PMID: 7893710
Catalytic role of 2'-hydroxyl groups within a group II intron active site.
Abramovitz DL, Friedman RA, Pyle AM. Abramovitz DL, et al. Science. 1996 Mar 8;271(5254):1410-3. doi: 10.1126/science.271.5254.1410. Science. 1996. PMID: 8596912
Branch-site selection in a group II intron mediated by active recognition of the adenine amino group and steric exclusion of non-adenine functionalities.
Liu Q, Green JB, Khodadadi A, Haeberli P, Beigelman L, Pyle AM. Liu Q, et al. J Mol Biol. 1997 Mar 21;267(1):163-71. doi: 10.1006/jmbi.1996.0845. J Mol Biol. 1997. PMID: 9096215
Group II intron splicing in vivo by first-step hydrolysis.
Podar M, Chu VT, Pyle AM, Perlman PS. Podar M, et al. Nature. 1998 Feb 26;391(6670):915-8. doi: 10.1038/36142. Nature. 1998. PMID: 9495347
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