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Sphingosine 1-phosphate signalling in mammalian cells.
Pyne S, Pyne NJ. Pyne S, et al. Among authors: pyne nj. Biochem J. 2000 Jul 15;349(Pt 2):385-402. doi: 10.1042/0264-6021:3490385. Biochem J. 2000. PMID: 10880336 Free PMC article. Review.
The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung.
Burns F, Rodger IW, Pyne NJ. Burns F, et al. Among authors: pyne nj. Biochem J. 1992 Apr 15;283 ( Pt 2)(Pt 2):487-91. doi: 10.1042/bj2830487. Biochem J. 1992. PMID: 1315515 Free PMC article.
Interaction of the catalytic subunit of protein kinase A with the lung type V cyclic GMP phosphodiesterase: modulation of non-catalytic binding sites.
Burns F, Pyne NJ. Burns F, et al. Among authors: pyne nj. Biochem Biophys Res Commun. 1992 Dec 30;189(3):1389-96. doi: 10.1016/0006-291x(92)90228-d. Biochem Biophys Res Commun. 1992. PMID: 1336365
Phosphorylation of the recombinant spliced variants of the alpha-sub-unit of the stimulatory guanine-nucleotide binding regulatory protein (Gs) by the catalytic sub-unit of protein kinase A.
Pyne NJ, Freissmuth M, Pyne S. Pyne NJ, et al. Among authors: pyne s. Biochem Biophys Res Commun. 1992 Jul 31;186(2):1081-6. doi: 10.1016/0006-291x(92)90857-h. Biochem Biophys Res Commun. 1992. PMID: 1497643
We suggest that, as for GS alpha phosphorylation by protein kinase C (Pyne et al., 1992), the guanine nucleotide-free form of GS alpha is the most likely substrate. ...
We suggest that, as for GS alpha phosphorylation by protein kinase C (Pyne et al., 1992), the guanine nucleotide-free form of GS alph …
Phosphorylation of the spliced variant forms of the recombinant stimulatory guanine-nucleotide-binding regulatory protein (Gs alpha) by protein kinase C.
Pyne NJ, Freissmuth M, Palmer S. Pyne NJ, et al. Biochem J. 1992 Jul 1;285 ( Pt 1)(Pt 1):333-8. doi: 10.1042/bj2850333. Biochem J. 1992. PMID: 1637317 Free PMC article.
Diabetes-induced alterations in the expression, functioning and phosphorylation state of the inhibitory guanine nucleotide regulatory protein Gi-2 in hepatocytes.
Bushfield M, Griffiths SL, Murphy GJ, Pyne NJ, Knowler JT, Milligan G, Parker PJ, Mollner S, Houslay MD. Bushfield M, et al. Among authors: pyne nj. Biochem J. 1990 Oct 15;271(2):365-72. doi: 10.1042/bj2710365. Biochem J. 1990. PMID: 1700700 Free PMC article.
Phorbol esters trigger the inactivation of the inhibitory quanine-nucleotide binding regulatory protein (Gi) in airway smooth muscle.
Pyne NJ, Shehnaz D, Rodger IW. Pyne NJ, et al. Biochem Soc Trans. 1991 Apr;19(2):75S. doi: 10.1042/bst019075s. Biochem Soc Trans. 1991. PMID: 1909669 No abstract available.
Insulin stimulates the tyrosyl phosphorylation and activation of the 52 kDa peripheral plasma-membrane cyclic AMP phosphodiesterase in intact hepatocytes.
Pyne NJ, Cushley W, Nimmo HG, Houslay MD. Pyne NJ, et al. Biochem J. 1989 Aug 1;261(3):897-904. doi: 10.1042/bj2610897. Biochem J. 1989. PMID: 2478121 Free PMC article.
Treatment of intact hepatocytes with either the phorbol ester TPA or glucagon elicits the phosphorylation and functional inactivation of the inhibitory guanine nucleotide regulatory protein Gi.
Pyne NJ, Murphy GJ, Milligan G, Houslay MD. Pyne NJ, et al. FEBS Lett. 1989 Jan 16;243(1):77-82. doi: 10.1016/0014-5793(89)81221-9. FEBS Lett. 1989. PMID: 2493392
Glucagon desensitization of adenylate cyclase and stimulation of inositol phospholipid metabolism does not involve the inhibitory guanine nucleotide regulatory protein Gi, which is inactivated upon challenge of hepatocytes with glucagon.
Murphy GJ, Gawler DJ, Milligan G, Wakelam MJ, Pyne NJ, Houslay MD. Murphy GJ, et al. Among authors: pyne nj. Biochem J. 1989 Apr 1;259(1):191-7. doi: 10.1042/bj2590191. Biochem J. 1989. PMID: 2497730 Free PMC article.
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