Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools.
Long J, Darroch P, Wan KF, Kong KC, Ktistakis N, Pyne NJ, Pyne S.
Long J, et al. Among authors: pyne s, pyne nj.
Biochem J. 2005 Oct 1;391(Pt 1):25-32. doi: 10.1042/BJ20050342.
Biochem J. 2005.
PMID: 15960610
Free PMC article.
We have shown previously that LPPs (lipid phosphate phosphatases) reduce the stimulation of the p42/p44 MAPK (p42/p44 mitogen-activated protein kinase) pathway by the GPCR (G-protein-coupled receptor) agonists S1P (sphingosine 1-phosphate) and LPA (lysophosphatidic acid) in serum …
We have shown previously that LPPs (lipid phosphate phosphatases) reduce the stimulation of the p42/p44 MAPK (p42/p44 mitogen-activated prot …