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Small Molecule Inhibitors of Protein Arginine Methyltransferases.
Hu H, Qian K, Ho MC, Zheng YG. Hu H, et al. Among authors: qian k. Expert Opin Investig Drugs. 2016;25(3):335-58. doi: 10.1517/13543784.2016.1144747. Epub 2016 Feb 16. Expert Opin Investig Drugs. 2016. PMID: 26789238 Free PMC article. Review.
Labeling: palladium brings proteins to life.
Qian K, Zheng YG. Qian K, et al. Nat Chem Biol. 2014 May;10(5):328-30. doi: 10.1038/nchembio.1507. Nat Chem Biol. 2014. PMID: 24743256 No abstract available.
Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.
Zhang L, Tran NT, Su H, Wang R, Lu Y, Tang H, Aoyagi S, Guo A, Khodadadi-Jamayran A, Zhou D, Qian K, Hricik T, Côté J, Han X, Zhou W, Laha S, Abdel-Wahab O, Levine RL, Raffel G, Liu Y, Chen D, Li H, Townes T, Wang H, Deng H, Zheng YG, Leslie C, Luo M, Zhao X. Zhang L, et al. Among authors: qian k. Elife. 2015 Nov 17;4:e07938. doi: 10.7554/eLife.07938. Elife. 2015. PMID: 26575292 Free PMC article.
Discovery of Decamidine as a New and Potent PRMT1 Inhibitor.
Zhang J, Qian K, Yan C, He M, Jassim BA, Ivanov I, Zheng YG. Zhang J, et al. Among authors: qian k. Medchemcomm. 2017 Feb 1;8(2):440-444. doi: 10.1039/C6MD00573J. Epub 2017 Jan 3. Medchemcomm. 2017. PMID: 28649316 Free PMC article.
Detection of PRMT1 inhibitors with stopped flow fluorescence.
Qian K, Hu H, Xu H, Zheng YG. Qian K, et al. Signal Transduct Target Ther. 2018 Mar 9;3:6. doi: 10.1038/s41392-018-0009-6. eCollection 2018. Signal Transduct Target Ther. 2018. PMID: 29535867 Free PMC article.
The dynamic conformational landscape of the protein methyltransferase SETD8.
Chen S, Wiewiora RP, Meng F, Babault N, Ma A, Yu W, Qian K, Hu H, Zou H, Wang J, Fan S, Blum G, Pittella-Silva F, Beauchamp KA, Tempel W, Jiang H, Chen K, Skene RJ, Zheng YG, Brown PJ, Jin J, Luo C, Chodera JD, Luo M. Chen S, et al. Among authors: qian k. Elife. 2019 May 13;8:e45403. doi: 10.7554/eLife.45403. Elife. 2019. PMID: 31081496 Free PMC article.
1,760 results