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2,664 results
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Genomic evidence for elevated mutation rates in highly expressed genes.
Park C, Qian W, Zhang J. Park C, et al. Among authors: qian w. EMBO Rep. 2012 Dec;13(12):1123-9. doi: 10.1038/embor.2012.165. Epub 2012 Nov 13. EMBO Rep. 2012. PMID: 23146897 Free PMC article.
Reduced intrinsic DNA curvature leads to increased mutation rate.
Duan C, Huan Q, Chen X, Wu S, Carey LB, He X, Qian W. Duan C, et al. Among authors: qian w. Genome Biol. 2018 Sep 14;19(1):132. doi: 10.1186/s13059-018-1525-y. Genome Biol. 2018. PMID: 30217230 Free PMC article.
The fitness landscape of a tRNA gene.
Li C, Qian W, Maclean CJ, Zhang J. Li C, et al. Among authors: qian w. Science. 2016 May 13;352(6287):837-40. doi: 10.1126/science.aae0568. Epub 2016 Apr 14. Science. 2016. PMID: 27080104 Free PMC article.
Genomic evidence for adaptation by gene duplication.
Qian W, Zhang J. Qian W, et al. Genome Res. 2014 Aug;24(8):1356-62. doi: 10.1101/gr.172098.114. Epub 2014 Jun 5. Genome Res. 2014. PMID: 24904045 Free PMC article.
The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast.
Qian W, Ma D, Xiao C, Wang Z, Zhang J. Qian W, et al. Cell Rep. 2012 Nov 29;2(5):1399-410. doi: 10.1016/j.celrep.2012.09.017. Epub 2012 Oct 25. Cell Rep. 2012. PMID: 23103169 Free PMC article.
Balanced codon usage optimizes eukaryotic translational efficiency.
Qian W, Yang JR, Pearson NM, Maclean C, Zhang J. Qian W, et al. PLoS Genet. 2012;8(3):e1002603. doi: 10.1371/journal.pgen.1002603. Epub 2012 Mar 29. PLoS Genet. 2012. PMID: 22479199 Free PMC article.
Measuring the evolutionary rate of protein-protein interaction.
Qian W, He X, Chan E, Xu H, Zhang J. Qian W, et al. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8725-30. doi: 10.1073/pnas.1104695108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555556 Free PMC article.
Maintenance of duplicate genes and their functional redundancy by reduced expression.
Qian W, Liao BY, Chang AY, Zhang J. Qian W, et al. Trends Genet. 2010 Oct;26(10):425-30. doi: 10.1016/j.tig.2010.07.002. Epub 2010 Aug 12. Trends Genet. 2010. PMID: 20708291 Free PMC article.
Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks.
He X, Qian W, Wang Z, Li Y, Zhang J. He X, et al. Among authors: qian w. Nat Genet. 2010 Mar;42(3):272-6. doi: 10.1038/ng.524. Epub 2010 Jan 24. Nat Genet. 2010. PMID: 20101242 Free PMC article.
Positive selection for elevated gene expression noise in yeast.
Zhang Z, Qian W, Zhang J. Zhang Z, et al. Among authors: qian w. Mol Syst Biol. 2009;5:299. doi: 10.1038/msb.2009.58. Epub 2009 Aug 18. Mol Syst Biol. 2009. PMID: 19690568 Free PMC article.
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