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Detection of secretion from single pancreatic beta-cells using extracellular fluorogenic reactions and confocal fluorescence microscopy.
Qian WJ, Aspinwall CA, Battiste MA, Kennedy RT. Qian WJ, et al. Anal Chem. 2000 Feb 15;72(4):711-7. doi: 10.1021/ac991085t. Anal Chem. 2000. PMID: 10701254
Spatial organization of Ca(2+) entry and exocytosis in mouse pancreatic beta-cells.
Qian WJ, Kennedy RT. Qian WJ, et al. Biochem Biophys Res Commun. 2001 Aug 17;286(2):315-21. doi: 10.1006/bbrc.2001.5379. Biochem Biophys Res Commun. 2001. PMID: 11500039
Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.
Aspinwall CA, Qian WJ, Roper MG, Kulkarni RN, Kahn CR, Kennedy RT. Aspinwall CA, et al. Among authors: qian wj. J Biol Chem. 2000 Jul 21;275(29):22331-8. doi: 10.1074/jbc.M909647199. J Biol Chem. 2000. PMID: 10764813
Correlated oscillations in glucose consumption, oxygen consumption, and intracellular free Ca(2+) in single islets of Langerhans.
Jung SK, Kauri LM, Qian WJ, Kennedy RT. Jung SK, et al. Among authors: qian wj. J Biol Chem. 2000 Mar 3;275(9):6642-50. doi: 10.1074/jbc.275.9.6642. J Biol Chem. 2000. PMID: 10692473
Divergent structure-activity relationships of structurally similar acetylcholinesterase inhibitors.
Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian W, Ekström F, Linusson A. Andersson CD, et al. J Med Chem. 2013 Oct 10;56(19):7615-24. doi: 10.1021/jm400990p. Epub 2013 Sep 19. J Med Chem. 2013. PMID: 23984975
Design, synthesis, and evaluation of N-acyl modified sialic acids as inhibitors of adenoviruses causing epidemic keratoconjunctivitis.
Johansson S, Nilsson E, Qian W, Guilligay D, Crepin T, Cusack S, Arnberg N, Elofsson M. Johansson S, et al. J Med Chem. 2009 Jun 25;52(12):3666-78. doi: 10.1021/jm801609s. J Med Chem. 2009. PMID: 19456100
An efficient and convenient Cu(OAc)(2)/air mediated oxidative coupling of azoles via C-H activation.
Li Y, Jin J, Qian W, Bao W. Li Y, et al. Org Biomol Chem. 2010 Jan 21;8(2):326-30. doi: 10.1039/b919396k. Epub 2009 Nov 9. Org Biomol Chem. 2010. PMID: 20066265
Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
Caraballo R, Saleeb M, Bauer J, Liaci AM, Chandra N, Storm RJ, Frängsmyr L, Qian W, Stehle T, Arnberg N, Elofsson M. Caraballo R, et al. Org Biomol Chem. 2015 Sep 21;13(35):9194-205. doi: 10.1039/c5ob01025j. Epub 2015 Jul 16. Org Biomol Chem. 2015. PMID: 26177934
Similar but different: thermodynamic and structural characterization of a pair of enantiomers binding to acetylcholinesterase.
Berg L, Niemiec MS, Qian W, Andersson CD, Wittung-Stafshede P, Ekström F, Linusson A. Berg L, et al. Angew Chem Int Ed Engl. 2012 Dec 14;51(51):12716-20. doi: 10.1002/anie.201205113. Epub 2012 Nov 19. Angew Chem Int Ed Engl. 2012. PMID: 23161758 No abstract available.
Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase.
Andersson CD, Hillgren JM, Lindgren C, Qian W, Akfur C, Berg L, Ekström F, Linusson A. Andersson CD, et al. J Comput Aided Mol Des. 2015 Mar;29(3):199-215. doi: 10.1007/s10822-014-9808-1. Epub 2014 Oct 29. J Comput Aided Mol Des. 2015. PMID: 25351962 Free PMC article.
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