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Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins.
Yoon KJ, Song G, Qian X, Pan J, Xu D, Rho HS, Kim NS, Habela C, Zheng L, Jacob F, Zhang F, Lee EM, Huang WK, Ringeling FR, Vissers C, Li C, Yuan L, Kang K, Kim S, Yeo J, Cheng Y, Liu S, Wen Z, Qin CF, Wu Q, Christian KM, Tang H, Jin P, Xu Z, Qian J, Zhu H, Song H, Ming GL. Yoon KJ, et al. Among authors: qin cf. Cell Stem Cell. 2017 Sep 7;21(3):349-358.e6. doi: 10.1016/j.stem.2017.07.014. Epub 2017 Aug 17. Cell Stem Cell. 2017. PMID: 28826723 Free PMC article.
Excretion of infectious Zika virus in urine.
Zhang FC, Li XF, Deng YQ, Tong YG, Qin CF. Zhang FC, et al. Among authors: qin cf. Lancet Infect Dis. 2016 Jun;16(6):641-642. doi: 10.1016/S1473-3099(16)30070-6. Epub 2016 May 13. Lancet Infect Dis. 2016. PMID: 27184420 No abstract available.
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model.
Li C, Deng YQ, Wang S, Ma F, Aliyari R, Huang XY, Zhang NN, Watanabe M, Dong HL, Liu P, Li XF, Ye Q, Tian M, Hong S, Fan J, Zhao H, Li L, Vishlaghi N, Buth JE, Au C, Liu Y, Lu N, Du P, Qin FX, Zhang B, Gong D, Dai X, Sun R, Novitch BG, Xu Z, Qin CF, Cheng G. Li C, et al. Among authors: qin cf, qin fx. Immunity. 2017 Mar 21;46(3):446-456. doi: 10.1016/j.immuni.2017.02.012. Epub 2017 Mar 14. Immunity. 2017. PMID: 28314593 Free PMC article.
Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction.
Li Z, Brecher M, Deng YQ, Zhang J, Sakamuru S, Liu B, Huang R, Koetzner CA, Allen CA, Jones SA, Chen H, Zhang NN, Tian M, Gao F, Lin Q, Banavali N, Zhou J, Boles N, Xia M, Kramer LD, Qin CF, Li H. Li Z, et al. Among authors: qin cf. Cell Res. 2017 Aug;27(8):1046-1064. doi: 10.1038/cr.2017.88. Epub 2017 Jul 7. Cell Res. 2017. PMID: 28685770 Free PMC article.
Zika virus directly infects peripheral neurons and induces cell death.
Oh Y, Zhang F, Wang Y, Lee EM, Choi IY, Lim H, Mirakhori F, Li R, Huang L, Xu T, Wu H, Li C, Qin CF, Wen Z, Wu QF, Tang H, Xu Z, Jin P, Song H, Ming GL, Lee G. Oh Y, et al. Among authors: qin cf. Nat Neurosci. 2017 Sep;20(9):1209-1212. doi: 10.1038/nn.4612. Epub 2017 Jul 31. Nat Neurosci. 2017. PMID: 28758997 Free PMC article.
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly.
Yuan L, Huang XY, Liu ZY, Zhang F, Zhu XL, Yu JY, Ji X, Xu YP, Li G, Li C, Wang HJ, Deng YQ, Wu M, Cheng ML, Ye Q, Xie DY, Li XF, Wang X, Shi W, Hu B, Shi PY, Xu Z, Qin CF. Yuan L, et al. Among authors: qin cf. Science. 2017 Nov 17;358(6365):933-936. doi: 10.1126/science.aam7120. Epub 2017 Sep 28. Science. 2017. PMID: 28971967
320 results