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At the interface of physics and biology.
Quake S. Quake S. Biotechniques. 2007 Jul;43(1):19. Biotechniques. 2007. PMID: 17695250 No abstract available.
Nanoliter reactors improve multiple displacement amplification of genomes from single cells.
Marcy Y, Ishoey T, Lasken RS, Stockwell TB, Walenz BP, Halpern AL, Beeson KY, Goldberg SM, Quake SR. Marcy Y, et al. PLoS Genet. 2007 Sep;3(9):1702-8. doi: 10.1371/journal.pgen.0030155. PLoS Genet. 2007. PMID: 17892324 Free PMC article.
Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood.
Fan HC, Blumenfeld YJ, Chitkara U, Hudgins L, Quake SR. Fan HC, et al. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16266-71. doi: 10.1073/pnas.0808319105. Epub 2008 Oct 6. Proc Natl Acad Sci U S A. 2008. PMID: 18838674 Free PMC article.
Microfluidic digital PCR enables rapid prenatal diagnosis of fetal aneuploidy.
Fan HC, Blumenfeld YJ, El-Sayed YY, Chueh J, Quake SR. Fan HC, et al. Am J Obstet Gynecol. 2009 May;200(5):543.e1-7. doi: 10.1016/j.ajog.2009.03.002. Am J Obstet Gynecol. 2009. PMID: 19375573 Free PMC article. Clinical Trial.
Single-molecule sequencing of an individual human genome.
Pushkarev D, Neff NF, Quake SR. Pushkarev D, et al. Nat Biotechnol. 2009 Sep;27(9):847-50. doi: 10.1038/nbt.1561. Epub 2009 Aug 10. Nat Biotechnol. 2009. PMID: 19668243 Free PMC article.
Digital MDA for enumeration of total nucleic acid contamination.
Blainey PC, Quake SR. Blainey PC, et al. Nucleic Acids Res. 2011 Mar;39(4):e19. doi: 10.1093/nar/gkq1074. Epub 2010 Nov 11. Nucleic Acids Res. 2011. PMID: 21071419 Free PMC article.
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