Preferential extravasation and accumulation of liposomal vincristine in tumor comparing to normal tissue enhances antitumor activity.
Shan S, Flowers C, Peltz CD, Sweet H, Maurer N, Kwon EJ, Krol A, Yuan F, Dewhirst MW.
Shan S, et al.
Cancer Chemother Pharmacol. 2006 Aug;58(2):245-55. doi: 10.1007/s00280-005-0145-x. Epub 2005 Dec 8.
Cancer Chemother Pharmacol. 2006.
PMID: 16341532
To quantitatively evaluate the extravasation, accumulation and selectivity to tumor tissues of liposomal vincristine (LV), dorsal skin-fold window chambers on athymic mice with or without LX-1, a human small cell lung cancer, xenograft implants …
To quantitatively evaluate the extravasation, accumulation and selectivity to tumor tissues of liposomal vincristine (LV), dor …