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Evolution of HIV integrase resistance mutations.
Quashie PK, Mesplède T, Wainberg MA. Quashie PK, et al. Curr Opin Infect Dis. 2013 Feb;26(1):43-9. doi: 10.1097/QCO.0b013e32835ba81c. Curr Opin Infect Dis. 2013. PMID: 23242340 Review.
Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.
Mesplède T, Osman N, Wares M, Quashie PK, Hassounah S, Anstett K, Han Y, Singhroy DN, Wainberg MA. Mesplède T, et al. Among authors: quashie pk. J Antimicrob Chemother. 2014 Oct;69(10):2733-40. doi: 10.1093/jac/dku199. Epub 2014 Jun 10. J Antimicrob Chemother. 2014. PMID: 24917583 Free PMC article.
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