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Principles and use of anti-CTLA4 antibody in human cancer immunotherapy.
Peggs KS, Quezada SA, Korman AJ, Allison JP. Peggs KS, et al. Among authors: quezada sa. Curr Opin Immunol. 2006 Apr;18(2):206-13. doi: 10.1016/j.coi.2006.01.011. Epub 2006 Feb 7. Curr Opin Immunol. 2006. PMID: 16464564 Review.
Immune Surveillance in Clinical Regression of Preinvasive Squamous Cell Lung Cancer.
Pennycuick A, Teixeira VH, AbdulJabbar K, Raza SEA, Lund T, Akarca AU, Rosenthal R, Kalinke L, Chandrasekharan DP, Pipinikas CP, Lee-Six H, Hynds RE, Gowers KHC, Henry JY, Millar FR, Hagos YB, Denais C, Falzon M, Moore DA, Antoniou S, Durrenberger PF, Furness AJ, Carroll B, Marceaux C, Asselin-Labat ML, Larson W, Betts C, Coussens LM, Thakrar RM, George J, Swanton C, Thirlwell C, Campbell PJ, Marafioti T, Yuan Y, Quezada SA, McGranahan N, Janes SM. Pennycuick A, et al. Among authors: quezada sa. Cancer Discov. 2020 Oct;10(10):1489-1499. doi: 10.1158/2159-8290.CD-19-1366. Epub 2020 Jul 20. Cancer Discov. 2020. PMID: 32690541
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
AbdulJabbar K, Raza SEA, Rosenthal R, Jamal-Hanjani M, Veeriah S, Akarca A, Lund T, Moore DA, Salgado R, Al Bakir M, Zapata L, Hiley CT, Officer L, Sereno M, Smith CR, Loi S, Hackshaw A, Marafioti T, Quezada SA, McGranahan N, Le Quesne J; TRACERx Consortium, Swanton C, Yuan Y. AbdulJabbar K, et al. Among authors: quezada sa. Nat Med. 2020 Jul;26(7):1054-1062. doi: 10.1038/s41591-020-0900-x. Epub 2020 May 27. Nat Med. 2020. PMID: 32461698
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi K, de Massy MR, Ismail M, Reading JL, Uddin I, Woolston A, Hatipoglu E, Oakes T, Rosenthal R, Peacock T, Ronel T, Noursadeghi M, Turati V, Furness AJS, Georgiou A, Wong YNS, Ben Aissa A, Sunderland MW, Jamal-Hanjani M, Veeriah S, Birkbak NJ, Wilson GA, Hiley CT, Ghorani E, Guerra-Assunção JA, Herrero J, Enver T, Hadrup SR, Hackshaw A, Peggs KS, McGranahan N, Swanton C; TRACERx consortium, Quezada SA, Chain B. Joshi K, et al. Among authors: quezada sa. Nat Med. 2019 Oct;25(10):1549-1559. doi: 10.1038/s41591-019-0592-2. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591606 Free PMC article.
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells.
Quezada SA, Peggs KS, Curran MA, Allison JP. Quezada SA, et al. J Clin Invest. 2006 Jul;116(7):1935-45. doi: 10.1172/JCI27745. Epub 2006 Jun 15. J Clin Invest. 2006. PMID: 16778987 Free PMC article.
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma.
Quezada SA, Peggs KS, Simpson TR, Shen Y, Littman DR, Allison JP. Quezada SA, et al. J Exp Med. 2008 Sep 1;205(9):2125-38. doi: 10.1084/jem.20080099. Epub 2008 Aug 25. J Exp Med. 2008. PMID: 18725522 Free PMC article.
Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy.
Peggs KS, Quezada SA, Allison JP. Peggs KS, et al. Among authors: quezada sa. Immunol Rev. 2008 Aug;224:141-65. doi: 10.1111/j.1600-065X.2008.00649.x. Immunol Rev. 2008. PMID: 18759925 Review.
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies.
Peggs KS, Quezada SA, Chambers CA, Korman AJ, Allison JP. Peggs KS, et al. Among authors: quezada sa. J Exp Med. 2009 Aug 3;206(8):1717-25. doi: 10.1084/jem.20082492. Epub 2009 Jul 6. J Exp Med. 2009. PMID: 19581407 Free PMC article.
Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists.
Peggs KS, Quezada SA, Allison JP. Peggs KS, et al. Among authors: quezada sa. Clin Exp Immunol. 2009 Jul;157(1):9-19. doi: 10.1111/j.1365-2249.2009.03912.x. Epub 2009 Feb 18. Clin Exp Immunol. 2009. PMID: 19659765 Free PMC article. Review.
Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS).
Simpson TR, Quezada SA, Allison JP. Simpson TR, et al. Among authors: quezada sa. Curr Opin Immunol. 2010 Jun;22(3):326-32. doi: 10.1016/j.coi.2010.01.001. Epub 2010 Jan 29. Curr Opin Immunol. 2010. PMID: 20116985 Review.
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