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Treatment and survival study in the C57BL/6J-APC(Min)/+(Min) mouse with R-flurbiprofen.
Life Sci. 2000 Jan 14;66(8):745-53. doi: 10.1016/s0024-3205(99)00645-1.
Life Sci. 2000.
PMID: 10680582
Mechanism of enhancement of intestinal ulcerogenicity of S-aryl propionic acids by their R-enantiomers in the rat.
Wechter WJ, McCracken JD, Kantoci D, Murray ED Jr, Quiggle D, Leipold D, Gibson K, Mineyama Y, Liu Y.
Wechter WJ, et al.
Dig Dis Sci. 1998 Jun;43(6):1264-74. doi: 10.1023/a:1018811908996.
Dig Dis Sci. 1998.
PMID: 9635617
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E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse.
Wechter WJ, Leipold DD, Murray ED Jr, Quiggle D, McCracken JD, Barrios RS, Greenberg NM.
Wechter WJ, et al. Among authors: quiggle d.
Cancer Res. 2000 Apr 15;60(8):2203-8.
Cancer Res. 2000.
PMID: 10786685
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Antiproliferative effects of the enantiomers of flurbiprofen.
McCracken JD, Wechter WJ, Liu Y, Chase RL, Kantoci D, Murray ED Jr, Quiggle DD, Mineyama Y.
McCracken JD, et al. Among authors: quiggle dd.
J Clin Pharmacol. 1996 Jun;36(6):540-5. doi: 10.1002/j.1552-4604.1996.tb05043.x.
J Clin Pharmacol. 1996.
PMID: 8809638
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R-flurbiprofen chemoprevention and treatment of intestinal adenomas in the APC(Min)/+ mouse model: implications for prophylaxis and treatment of colon cancer.
Wechter WJ, Kantoci D, Murray ED Jr, Quiggle DD, Leipold DD, Gibson KM, McCracken JD.
Wechter WJ, et al. Among authors: quiggle dd.
Cancer Res. 1997 Oct 1;57(19):4316-24.
Cancer Res. 1997.
PMID: 9331093
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Bioinversion of R-flurbiprofen to S-flurbiprofen at various dose levels in rat, mouse, and monkey.
Leipold DD, Kantoci D, Murray ED Jr, Quiggle DD, Wechter WJ.
Leipold DD, et al. Among authors: quiggle dd.
Chirality. 2004 Jul;16(6):379-87. doi: 10.1002/chir.20053.
Chirality. 2004.
PMID: 15190583
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Endogenous natriuretic factors. 5. Synthesis and biological activity of a natriuretic metabolite of diltiazem and its derivatives.
Kantoci D, Murray ED Jr, Quiggle DD, Wechter WJ.
Kantoci D, et al. Among authors: quiggle dd.
J Med Chem. 1996 Mar 15;39(6):1196-1200. doi: 10.1021/jm950559n.
J Med Chem. 1996.
PMID: 8632425
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Endogenous natriuretic factors 7: biospecificity of a natriuretic gamma-tocopherol metabolite LLU-alpha.
Murray ED Jr, Wechter WJ, Kantoci D, Wang WH, Pham T, Quiggle DD, Gibson KM, Leipold D, Anner BM.
Murray ED Jr, et al. Among authors: quiggle dd.
J Pharmacol Exp Ther. 1997 Aug;282(2):657-62.
J Pharmacol Exp Ther. 1997.
PMID: 9262327
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