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Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization.
Beutler LR, Wanat MJ, Quintana A, Sanz E, Bamford NS, Zweifel LS, Palmiter RD. Beutler LR, et al. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4206-11. doi: 10.1073/pnas.1101424108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368124 Free PMC article.
Fatal breathing dysfunction in a mouse model of Leigh syndrome.
Quintana A, Zanella S, Koch H, Kruse SE, Lee D, Ramirez JM, Palmiter RD. Quintana A, et al. J Clin Invest. 2012 Jul;122(7):2359-68. doi: 10.1172/JCI62923. Epub 2012 Jun 1. J Clin Invest. 2012. PMID: 22653057 Free PMC article.
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome.
Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, Morgan PG, Sedensky MM, Kaeberlein M. Johnson SC, et al. Science. 2013 Dec 20;342(6165):1524-8. doi: 10.1126/science.1244360. Epub 2013 Nov 14. Science. 2013. PMID: 24231806 Free PMC article.
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