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The microRNA miR-196b acts as a tumor suppressor in Cdx2-driven acute myeloid leukemia.
Rawat VPS, Götze M, Rasalkar A, Vegi NM, Ihme S, Thoene S, Pastore A, Bararia D, Döhner H, Döhner K, Feuring-Buske M, Quintanilla-Fend L, Buske C. Rawat VPS, et al. Among authors: quintanilla fend l. Haematologica. 2020 Jun;105(6):e285-e289. doi: 10.3324/haematol.2019.223297. Epub 2019 Sep 26. Haematologica. 2020. PMID: 31558674 Free PMC article. No abstract available.
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.
Bamezai S, Demir D, Pulikkottil AJ, Ciccarone F, Fischbein E, Sinha A, Borga C, Te Kronnie G, Meyer LH, Mohr F, Götze M, Caiafa P, Debatin KM, Döhner K, Döhner H, González-Menéndez I, Quintanilla-Fend L, Herold T, Jeremias I, Feuring-Buske M, Buske C, Rawat VPS. Bamezai S, et al. Among authors: quintanilla fend l. Leukemia. 2021 Feb;35(2):389-403. doi: 10.1038/s41375-020-0864-3. Epub 2020 May 15. Leukemia. 2021. PMID: 32409690
The leukemogenicity of Hoxa9 depends on alternative splicing.
Stadler CR, Vegi N, Mulaw MA, Edmaier KE, Rawat VP, Dolnik A, Bullinger L, Heilmeier B, Quintanilla-Fend L, Spiekermann K, Hiddemann W, Döhner K, Döhner H, Feuring-Buske M, Buske C. Stadler CR, et al. Leukemia. 2014 Sep;28(9):1838-43. doi: 10.1038/leu.2014.74. Epub 2014 Feb 18. Leukemia. 2014. PMID: 24535405
Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus.
Cusan M, Vegi NM, Mulaw MA, Bamezai S, Kaiser LM, Deshpande AJ, Greif PA, Quintanilla-Fend L, Göllner S, Müller-Tidow C, Humphries KR, Armstrong SA, Hiddemann W, Feuring-Buske M, Buske C. Cusan M, et al. Among authors: quintanilla fend l. Blood. 2017 Jan 19;129(3):319-323. doi: 10.1182/blood-2016-04-706978. Epub 2016 Nov 8. Blood. 2017. PMID: 27827825 Free article.
T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts.
Feucht J, Kayser S, Gorodezki D, Hamieh M, Döring M, Blaeschke F, Schlegel P, Bösmüller H, Quintanilla-Fend L, Ebinger M, Lang P, Handgretinger R, Feuchtinger T. Feucht J, et al. Among authors: quintanilla fend l. Oncotarget. 2016 Nov 22;7(47):76902-76919. doi: 10.18632/oncotarget.12357. Oncotarget. 2016. PMID: 27708227 Free PMC article.
Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis.
Geue S, Aurbach K, Manke MC, Manukjan G, Münzer P, Stegner D, Brähler C, Walker-Allgaier B, Märklin M, Borst CE, Quintanilla-Fend L, Rath D, Geisler T, Salih HR, Seizer P, Lang F, Nieswandt B, Gawaz M, Schulze H, Pleines I, Borst O. Geue S, et al. Among authors: quintanilla fend l. Blood. 2019 Nov 21;134(21):1847-1858. doi: 10.1182/blood.2019000185. Blood. 2019. PMID: 31578203 Free article.
PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo.
Niessner H, Schmitz J, Tabatabai G, Schmid AM, Calaminus C, Sinnberg T, Weide B, Eigentler TK, Garbe C, Schittek B, Quintanilla-Fend L, Bender B, Mai M, Praetorius C, Beissert S, Schackert G, Muders MH, Meinhardt M, Baretton GB, Dummer R, Flaherty K, Pichler BJ, Kulms D, Westphal D, Meier F. Niessner H, et al. Among authors: quintanilla fend l. Clin Cancer Res. 2016 Dec 1;22(23):5818-5828. doi: 10.1158/1078-0432.CCR-16-0064. Epub 2016 Jun 15. Clin Cancer Res. 2016. PMID: 27307593 Free article.
28 results