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Has the new TNM classification for colorectal cancer improved care?
Nagtegaal ID, Quirke P, Schmoll HJ. Nagtegaal ID, et al. Nat Rev Clin Oncol. 2011 Oct 18;9(2):119-23. doi: 10.1038/nrclinonc.2011.157. Nat Rev Clin Oncol. 2011. PMID: 22009076 Review.
European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Annotations of colorectal lesions.
Vieth M, Quirke P, Lambert R, von Karsa L, Risio M; International Agency for Research on Cancer. Vieth M, et al. Endoscopy. 2012 Sep;44 Suppl 3:SE131-9. doi: 10.1055/s-0032-1309798. Epub 2012 Sep 25. Endoscopy. 2012. PMID: 23012116
What is the role for the circumferential margin in the modern treatment of rectal cancer?
Nagtegaal ID, Quirke P. Nagtegaal ID, et al. J Clin Oncol. 2008 Jan 10;26(2):303-12. doi: 10.1200/JCO.2007.12.7027. J Clin Oncol. 2008. PMID: 18182672 Review.
RESULTS: We demonstrate that, after neoadjuvant therapy (both radiotherapy and radiochemotherapy), the predictive value of the CRM for local recurrence is significantly higher than when no preoperative therapy has been applied (hazard ratio [HR] = 6.3 v 2.0, respectively; P
RESULTS: We demonstrate that, after neoadjuvant therapy (both radiotherapy and radiochemotherapy), the predictive value of the CRM for local …
EphB2 is a prognostic factor in colorectal cancer.
Jubb AM, Zhong F, Bheddah S, Grabsch HI, Frantz GD, Mueller W, Kavi V, Quirke P, Polakis P, Koeppen H. Jubb AM, et al. Clin Cancer Res. 2005 Jul 15;11(14):5181-7. doi: 10.1158/1078-0432.CCR-05-0143. Clin Cancer Res. 2005. PMID: 16033834
Patients whose tumor stained 2+ for EphB2 expression (versus 0/1+) exhibited significantly prolonged overall survival: mean duration of survival, 2,514 versus 1,044 days; hazard ratio, 0.45; 95% confidence interval, 0.18 to 0.95 (P = 0.035). ...
Patients whose tumor stained 2+ for EphB2 expression (versus 0/1+) exhibited significantly prolonged overall survival: mean duration of surv …
Prediction of the response of colorectal cancer to systemic therapy.
Adlard JW, Richman SD, Seymour MT, Quirke P. Adlard JW, et al. Lancet Oncol. 2002 Feb;3(2):75-82. doi: 10.1016/s1470-2045(02)00648-4. Lancet Oncol. 2002. PMID: 11902527 Review.
Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control.
Nagtegaal ID, van de Velde CJ, van der Worp E, Kapiteijn E, Quirke P, van Krieken JH; Cooperative Clinical Investigators of the Dutch Colorectal Cancer Group. Nagtegaal ID, et al. J Clin Oncol. 2002 Apr 1;20(7):1729-34. doi: 10.1200/JCO.2002.07.010. J Clin Oncol. 2002. PMID: 11919228 Clinical Trial.
Patients in this group had an increased risk for local and distant recurrence, 36.1% v. 20.3% recurrence in the group with a complete mesorectum (P =.02). ...
Patients in this group had an increased risk for local and distant recurrence, 36.1% v. 20.3% recurrence in the group with a complete mesore …
Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016.
Lugli A, Kirsch R, Ajioka Y, Bosman F, Cathomas G, Dawson H, El Zimaity H, Fléjou JF, Hansen TP, Hartmann A, Kakar S, Langner C, Nagtegaal I, Puppa G, Riddell R, Ristimäki A, Sheahan K, Smyrk T, Sugihara K, Terris B, Ueno H, Vieth M, Zlobec I, Quirke P. Lugli A, et al. Mod Pathol. 2017 Sep;30(9):1299-1311. doi: 10.1038/modpathol.2017.46. Epub 2017 May 26. Mod Pathol. 2017. PMID: 28548122 Review.
Pathology is a necessary and informative tool in oncology clinical trials.
Nagtegaal ID, West NP, van Krieken JH, Quirke P. Nagtegaal ID, et al. J Pathol. 2014 Jan;232(2):185-9. doi: 10.1002/path.4261. J Pathol. 2014. PMID: 24037805 Review.
Annex to Quirke et al. Quality assurance in pathology in colorectal cancer screening and diagnosis: annotations of colorectal lesions.
Vieth M, Quirke P, Lambert R, von Karsa L, Risio M. Vieth M, et al. Virchows Arch. 2011 Jan;458(1):21-30. doi: 10.1007/s00428-010-0997-2. Virchows Arch. 2011. PMID: 21061132 Free PMC article. Review.
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