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Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome.
Rizza S, Muniyappa R, Iantorno M, Kim JA, Chen H, Pullikotil P, Senese N, Tesauro M, Lauro D, Cardillo C, Quon MJ. Rizza S, et al. Among authors: quon mj. J Clin Endocrinol Metab. 2011 May;96(5):E782-92. doi: 10.1210/jc.2010-2879. Epub 2011 Feb 23. J Clin Endocrinol Metab. 2011. PMID: 21346065 Free PMC article. Clinical Trial.
Insulin action and insulin resistance in vascular endothelium.
Muniyappa R, Quon MJ. Muniyappa R, et al. Among authors: quon mj. Curr Opin Clin Nutr Metab Care. 2007 Jul;10(4):523-30. doi: 10.1097/MCO.0b013e32819f8ecd. Curr Opin Clin Nutr Metab Care. 2007. PMID: 17563474 Review.
Cardiovascular actions of insulin.
Muniyappa R, Montagnani M, Koh KK, Quon MJ. Muniyappa R, et al. Among authors: quon mj. Endocr Rev. 2007 Aug;28(5):463-91. doi: 10.1210/er.2007-0006. Epub 2007 May 24. Endocr Rev. 2007. PMID: 17525361 Review.
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