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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F. Bruchard M, et al. Among authors: rebe c. Nat Med. 2013 Jan;19(1):57-64. doi: 10.1038/nm.2999. Epub 2012 Dec 2. Nat Med. 2013. PMID: 23202296
Involvement of caspase-2 long isoform in Fas-mediated cell death of human leukemic cells.
Droin N, Bichat F, Rébé C, Wotawa A, Sordet O, Hammann A, Bertrand R, Solary E. Droin N, et al. Among authors: rebe c. Blood. 2001 Mar 15;97(6):1835-44. doi: 10.1182/blood.v97.6.1835. Blood. 2001. PMID: 11238127
In leukemic cells transfected with an empty vector, anti-Fas Ab treatment activated caspase-8, decreased the expression of the BH3 domain-only protein Bid, triggered the release of cytochrome c from the mitochondria to the cytosol, and activated caspase-3. ...Down-regulati …
In leukemic cells transfected with an empty vector, anti-Fas Ab treatment activated caspase-8, decreased the expression of the BH3 domain-on …
Modulation of apoptotic pathways triggered by cytotoxic agents.
Solary E, Plenchette S, Sordet O, Rébé C, Ducoroy P, Filomenko R, Bruey JM, Droin N, Corcos L. Solary E, et al. Among authors: rebe c. Therapie. 2001 Sep-Oct;56(5):511-8. Therapie. 2001. PMID: 11806287 Review.
The main pathway from specific damage induced by the drug to apoptosis involves activation of caspases in the cytosol by pro-apoptotic molecules such as cytochrome c released from the mitochondria. ...
The main pathway from specific damage induced by the drug to apoptosis involves activation of caspases in the cytosol by pro-apoptotic molec …
Specific involvement of caspases in the differentiation of monocytes into macrophages.
Sordet O, Rébé C, Plenchette S, Zermati Y, Hermine O, Vainchenker W, Garrido C, Solary E, Dubrez-Daloz L. Sordet O, et al. Among authors: rebe c. Blood. 2002 Dec 15;100(13):4446-53. doi: 10.1182/blood-2002-06-1778. Epub 2002 Aug 8. Blood. 2002. PMID: 12393560
Differentiation-associated caspase activation involves the release of cytochrome c from the mitochondria and leads to the cleavage of the protein acinus while the poly(ADP-ribose)polymerase remains uncleaved. ...
Differentiation-associated caspase activation involves the release of cytochrome c from the mitochondria and leads to the cleavage of …
Bcl-2 proteins: targets and tools for chemosensitisation of tumor cells.
Bettaieb A, Dubrez-Daloz L, Launay S, Plenchette S, Rébé C, Cathelin S, Solary E. Bettaieb A, et al. Among authors: rebe c. Curr Med Chem Anticancer Agents. 2003 Jul;3(4):307-18. doi: 10.2174/1568011033482396. Curr Med Chem Anticancer Agents. 2003. PMID: 12769775 Review.
Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells.
Delmas D, Rébé C, Lacour S, Filomenko R, Athias A, Gambert P, Cherkaoui-Malki M, Jannin B, Dubrez-Daloz L, Latruffe N, Solary E. Delmas D, et al. Among authors: rebe c. J Biol Chem. 2003 Oct 17;278(42):41482-90. doi: 10.1074/jbc.M304896200. Epub 2003 Aug 5. J Biol Chem. 2003. PMID: 12902349
Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event.
Plenchette S, Cathelin S, Rébé C, Launay S, Ladoire S, Sordet O, Ponnelle T, Debili N, Phan TH, Padua RA, Dubrez-Daloz L, Solary E. Plenchette S, et al. Among authors: rebe c. Blood. 2004 Oct 1;104(7):2035-43. doi: 10.1182/blood-2004-01-0065. Epub 2004 Jun 8. Blood. 2004. PMID: 15187025
When these cells undergo differentiation under phorbol ester exposure, c-IAP1 translocates to the cytoplasmic side of the Golgi apparatus. ...Altogether, these observations associate c-IAP1 cellular location with cell differentiation, which opens new perspectives on …
When these cells undergo differentiation under phorbol ester exposure, c-IAP1 translocates to the cytoplasmic side of the Golgi appar …
Caspase-10 involvement in cytotoxic drug-induced apoptosis of tumor cells.
Filomenko R, Prévotat L, Rébé C, Cortier M, Jeannin JF, Solary E, Bettaieb A. Filomenko R, et al. Among authors: rebe c. Oncogene. 2006 Dec 7;25(58):7635-45. doi: 10.1038/sj.onc.1209733. Epub 2006 Jun 12. Oncogene. 2006. PMID: 16767158
The extrinsic pathway to apoptosis is not involved in drug-induced caspase-10 activation that occurs downstream of Bax redistribution to mitochondria and cytochrome c release from this organelle. siRNA-mediated downregulation of Apaf-1 prevents etoposide-mediated activatio …
The extrinsic pathway to apoptosis is not involved in drug-induced caspase-10 activation that occurs downstream of Bax redistribution to mit …
Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation.
Rébé C, Cathelin S, Launay S, Filomenko R, Prévotat L, L'Ollivier C, Gyan E, Micheau O, Grant S, Dubart-Kupperschmitt A, Fontenay M, Solary E. Rébé C, et al. Blood. 2007 Feb 15;109(4):1442-50. doi: 10.1182/blood-2006-03-011585. Epub 2006 Oct 17. Blood. 2007. PMID: 17047155 Free PMC article.
7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent.
Lemaire-Ewing S, Berthier A, Royer MC, Logette E, Corcos L, Bouchot A, Monier S, Prunet C, Raveneau M, Rébé C, Desrumaux C, Lizard G, Néel D. Lemaire-Ewing S, et al. Among authors: rebe c. Cell Biol Toxicol. 2009 Apr;25(2):127-39. doi: 10.1007/s10565-008-9063-0. Epub 2008 Mar 4. Cell Biol Toxicol. 2009. PMID: 18317936
ERK activation led to an increase of c-fos mRNA and/or an activation of c-fos. Luciferase reporter gene assay using constructs of the human IL-8 gene promoter and Transam assay revealed the involvement of the AP-1 transcription factor in oxysterol-dependent IL-8 sec …
ERK activation led to an increase of c-fos mRNA and/or an activation of c-fos. Luciferase reporter gene assay using constructs …
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