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Identification and characterization of an IkappaB kinase.
Régnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M. Régnier CH, et al. Cell. 1997 Jul 25;90(2):373-83. doi: 10.1016/s0092-8674(00)80344-x. Cell. 1997. PMID: 9244310
NF-kappa B activation by tumor necrosis factor and interleukin-1.
Cao Z, Tanaka M, Regnier C, Rothe M, Yamit-hezi A, Woronicz JD, Fuentes ME, Durnin MH, Dalrymple SA, Goeddel DV. Cao Z, et al. Among authors: regnier c. Cold Spring Harb Symp Quant Biol. 1999;64:473-83. doi: 10.1101/sqb.1999.64.473. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232324 Review. No abstract available.
Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2.
Song HY, Régnier CH, Kirschning CJ, Goeddel DV, Rothe M. Song HY, et al. Among authors: regnier ch. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9792-6. doi: 10.1073/pnas.94.18.9792. Proc Natl Acad Sci U S A. 1997. PMID: 9275204 Free PMC article.
The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition.
Bardet M, Unterreiner A, Malinverni C, Lafossas F, Vedrine C, Boesch D, Kolb Y, Kaiser D, Glück A, Schneider MA, Katopodis A, Renatus M, Simic O, Schlapbach A, Quancard J, Régnier CH, Bold G, Pissot-Soldermann C, Carballido JM, Kovarik J, Calzascia T, Bornancin F. Bardet M, et al. Among authors: regnier ch. Immunol Cell Biol. 2018 Jan;96(1):81-99. doi: 10.1111/imcb.1018. Epub 2017 Dec 21. Immunol Cell Biol. 2018. PMID: 29359407
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.
Klein T, Fung SY, Renner F, Blank MA, Dufour A, Kang S, Bolger-Munro M, Scurll JM, Priatel JJ, Schweigler P, Melkko S, Gold MR, Viner RI, Régnier CH, Turvey SE, Overall CM. Klein T, et al. Among authors: regnier ch. Nat Commun. 2015 Nov 3;6:8777. doi: 10.1038/ncomms9777. Nat Commun. 2015. PMID: 26525107 Free PMC article.
Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma.
Régnier CH, Tomasetto C, Moog-Lutz C, Chenard MP, Wendling C, Basset P, Rio MC. Régnier CH, et al. J Biol Chem. 1995 Oct 27;270(43):25715-21. doi: 10.1074/jbc.270.43.25715. J Biol Chem. 1995. PMID: 7592751
Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2.
Arenas-Ramirez N, Zou C, Popp S, Zingg D, Brannetti B, Wirth E, Calzascia T, Kovarik J, Sommer L, Zenke G, Woytschak J, Regnier CH, Katopodis A, Boyman O. Arenas-Ramirez N, et al. Among authors: regnier ch. Sci Transl Med. 2016 Nov 30;8(367):367ra166. doi: 10.1126/scitranslmed.aag3187. Sci Transl Med. 2016. PMID: 27903862
Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805.
Baffert F, Régnier CH, De Pover A, Pissot-Soldermann C, Tavares GA, Blasco F, Brueggen J, Chène P, Drueckes P, Erdmann D, Furet P, Gerspacher M, Lang M, Ledieu D, Nolan L, Ruetz S, Trappe J, Vangrevelinghe E, Wartmann M, Wyder L, Hofmann F, Radimerski T. Baffert F, et al. Among authors: regnier ch. Mol Cancer Ther. 2010 Jul;9(7):1945-55. doi: 10.1158/1535-7163.MCT-10-0053. Epub 2010 Jun 29. Mol Cancer Ther. 2010. PMID: 20587663
N-aryl-piperidine-4-carboxamides as a novel class of potent inhibitors of MALT1 proteolytic activity.
Schlapbach A, Revesz L, Pissot Soldermann C, Zoller T, Régnier CH, Bornancin F, Radimerski T, Blank J, Schuffenhauer A, Renatus M, Erbel P, Melkko S, Heng R, Simic O, Endres R, Wartmann M, Quancard J. Schlapbach A, et al. Among authors: regnier ch. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2153-2158. doi: 10.1016/j.bmcl.2018.05.017. Epub 2018 May 9. Bioorg Med Chem Lett. 2018. PMID: 29759726
Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.
Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil-Allaoui I, Rush JS, Smith PA, Bigaud M, Junker-Walker U, Burkhart C, Dawson J, Niwa S, Katopodis A, Nuesslein-Hildesheim B, Weckbecker G, Zenke G, Kinzel B, Traggiai E, Brenner D, Brüstle A, St Paul M, Zamurovic N, McCoy KD, Rolink A, Régnier CH, Mak TW, Ohashi PS, Patel DD, Calzascia T. Bornancin F, et al. Among authors: regnier ch. J Immunol. 2015 Apr 15;194(8):3723-34. doi: 10.4049/jimmunol.1402254. Epub 2015 Mar 11. J Immunol. 2015. PMID: 25762782 Free article.
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