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Lean body mass is a major determinant of levothyroxine dosage in the treatment of thyroid diseases.
Santini F, Pinchera A, Marsili A, Ceccarini G, Castagna MG, Valeriano R, Giannetti M, Taddei D, Centoni R, Scartabelli G, Rago T, Mammoli C, Elisei R, Vitti P. Santini F, et al. Among authors: centoni r. J Clin Endocrinol Metab. 2005 Jan;90(1):124-7. doi: 10.1210/jc.2004-1306. Epub 2004 Oct 13. J Clin Endocrinol Metab. 2005. PMID: 15483074

There was a much stronger association between the l-T(4) dosage and lean body mass (P < 0.001, r = 0.667) compared with fat mass (P = 0.023, r = 0.26). Measurement of regional tissue composition showed peripheral lean mass as the best correlate with the dose of l

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There was a much stronger association between the l-T(4) dosage and lean body mass (P < 0.001, r = 0.667) compared with fat mass (

…
Analyses of data of patients with Thrombotic Microangiopathy in the WAA registry.
Mörtzell M, Berlin G, Nilsson T, Axelsson CG, Efvergren M, Audzijoni J, Griskevicius A, Ptak J, Blaha M, Tomsova H, Liumbruno GM, Centoni P, Newman E, Eloot S, Dhondt A, Tomaz J, Witt V, Rock G, Stegmayr B. Mörtzell M, et al. Among authors: centoni p. Transfus Apher Sci. 2011 Oct;45(2):125-31. doi: 10.1016/j.transci.2011.07.001. Epub 2011 Sep 7. Transfus Apher Sci. 2011. PMID: 21903476
There was an inverse correlation between the ADAMTS13 level and the antibody titer (r=-0.47, p=0.034). CONCLUSIONS: Patients with TMA have an increased risk for moderate and severe AE compared to the general apheresis population. ...
There was an inverse correlation between the ADAMTS13 level and the antibody titer (r=-0.47, p=0.034). CONCLUSIONS: Patients with TMA …